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Key Points• Phase I study showed that intraventricular rituximab plus methotrexate is feasible and active in the treatment of refractory CNS lymphoma.

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The rate of SpO2 decline increases as SpO2 decreases, with an inflection point occurring around 93%. Intubation attempts below this value are almost always associated with subsequent desaturation, suggesting that BVM should be used prior to laryngoscopy in these patients.

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Use of this assessment tool for interpretation of EFAST images showed face and content validity. Score trends showed a significant correlation with existing ACEP guidelines, ultrasound experience, and the training level. Scores continued to improve with experience beyond ACEP recommended guidelines.