Greater than 99·5% of collections contain no viable, aerobic bacteria in solution at the time of early culture testing. For every confirmed positive contaminated collection detected, there are at most 19 collections with low concentrations of dormant bacteria that are not readily detected by early BacT/ALERT™ culture.
The safety initiative with new selection criteria for EBV led to decreased complications among donors 16 to 18 years old, such that the risk for 16-year-olds was no longer different from that observed for 19-year-olds in the analysis stratified by age, sex, and donation status.
The risk of TRALI after plasma transfusion has been markedly reduced for blood groups A, B, and O but not for AB, reflecting continued reliance on group AB plasma from female donors to meet increasing demand.
Objetivo: describir y correlacionar las variantes genéticas, farmacogenéticas, características clínicas y desenlaces en una cohorte de pacientes pediátricos con leucemia mieloide aguda de novo en dos centros de cáncer pediátrico de Bogotá D.C. Materiales y métodos: estudio observacional descriptivo de cohorte; se incluyeron 51 muestras de pacientes pediátricos con diagnóstico confirmado de LMA de novo. A todas las muestras se les realizó estudio de citogenética convencional y molecular, pruebas de biología molecular, secuencia de nueva generación (panel para LMA) y análisis de variantes farmacogenéticas en ABCB1, CDA, DCK, GSTT1 y GSTM1 mediante SNaPshot y PCR. Variantes genéticas, características clínicas, eventos y desenlaces fueron evaluados mediante odds ratio, Chi cuadrado y curvas de supervivencia.
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