Human Coronaviruses (HCoV) exhibit positive single stranded RNA genome with enveloped nucleocapsid. Coronavirus belongs to the family Coronaviridae, originated from avian and mammalian species causes upper respiratory tract infection in humans by novel HCoVs viruses named as HCoV-HKU1, HCoV-NL63 but predominant species is Middle East respiratory syndrome (MERS-CoV) across the world. HCoV-HKU1 sp. is associated with chronic pulmonary disease, while HCoV-NL63 causes upper and lower respiratory tract disease in both children and adults, but most recent one was MERS-CoV, which caused acute pneumonia and occasional renal failure. The novel coronavirus SARS-CoV-2 is a new strain that causes the Coronavirus Disease 2019 (COVID-19) as named by the World Health Organization. According to the recent world statistics report about the COVID-19 cases approx. 101,500 confirmed cases and 3,500 death cases appeared. And mostly, a case of infection with CoV was identified in Wuhan, China. Structurally viral genome constitutes of 2/3rd of replicase gene encoding ORFs regions and rest of the 1/3rd region of genome form the structural proteins. The aim of the study was to understand the viral genetic systems in order to facilitate the genetic manipulation of the viral genome and to know the fundamental mechanism during the viral replication, facilitating the development of antidotes against the virus.

Background: India has 8.6% elderly population which is going to increase to 12% by 2025. Government of India is providing for the elderly through various social security and welfare schemes as well as legislations. But various studies, mostly in rural areas have shown that the awareness regarding these schemes was poor and incomplete. Utilization of schemes by the beneficiaries was even poorer. Very few studies have assessed the same in urban areas. Aims & Objectives: To assess the awareness and utilization of geriatric welfare schemes and factors associated with them among urban elderly. Material & Methods: The study was conducted in urban field practice area of Dept of Community Medicine, SMS&R, Greater Noida. 402 elderly living in slums of Bhangel, Noida, were interviewed using semi structured questionnaire assuming 50% awareness levels in the urban area with 10% relative precision and 95% confidence interval. Results: Awareness regarding any one scheme was 31.6%, of whom only one fourth subjects knew about more than one scheme. Among those who knew about the schemes, only 40% were utilizing them. The awareness as well as utilization was found to be significantly associated with religion, caste and educational status of the subject. Conclusion: The study shows poor awareness and even poorer utilization of geriatric welfare schemes among elderly people of urban slums. Further studies are required for judging the influencing factors.

Background: Psychological well-being (PWB) is affected by age, physical health, personality, life experiences, socioeconomic status, and culture. Age is an important social determinant of health and age-based analysis is necessary to rectify one’s health and health care. Aims and Objectives: This study aims to assess the PWB of college students and to determine the correlation between age and PWB aspects. Materials and Methods: This cross-sectional study was conducted among 210 college students selected by simple random sampling. Ryff’s PWB scale, a 42-item version used for the assessment of PWB, and data were collected by self-administering questionnaires. Statistical Analysis: Internal consistency of the scale was estimated and descriptive statistics, independent samples t-test, and regression analysis were applied. Results: The mean age of the participants was 19.41±1.69 years and 61% were male. Cronbach’s alpha coefficient for internal consistency of Ryff’s PWB scale was 0.814 in this study. The mean of PWB was 205.42±11.04 and ≥20 years scored higher in all the parameters of PWB than <20 years, differences were (t=3.62, P=0.001) significant. Simple linear regression showed that age was a highly significant (P=0.002) predictor of PWB. Conclusion: The study illustrated that students of 20 years or more had better PWB in terms of all dimensions than <20 years-, and also suggested the need for future research, like, to deepen on the conceptual and relations between age and PWB, and to analyze the impact that social changes have toward age group on PWB.

Introduction: Shoulder arthroplasty offers pain relief and improvement in patients of shoulder arthritis. It need proper fixation of glenoid cavity to prevent loosening, a common cause for surgery. As glenoid cavity is small, it permits only a tight spot for limited fixation devices. So, knowledge of the morphological data of various parameters of glenoid cavity is of utter importance. Materials and Methods: An observational cross-Sectional study was done on 66 unpaired human scapulae. They belong to adult population of North India and of unknown sex. Superior-inferior diameter and Anterior-posterior diameter of maximum distance at the glenoid cavity were measured and based on these measurements index of glenoid cavity calculated. Result and Discussion: The shape of the glenoid cavity was classified on basis of the presence or absence of a notch on the glenoid rim as pear shaped, inverted comma shaped and oval shaped. All the parameters exhibit a greater value for the right side. The ethnic and racial variations could be the explanation for difference seen between the values of present study and that of other workers. The above mentioned parameters may be taken into consideration while doing shoulder arthroplasty and designing glenoid prostheses for North Indian population. Conclusion:Extensive and detail knowledge of various data of the glenoid cavity measurements is important for the anatomists, orthopaedicians, prosthetists, and anthropologists.

Background: Morphometric dimensions of ear plays a very important role in plastic surgery and prosthetics. This study aimed to determine different morphometric parameters of both ear and to provide information regarding age related changes. Methods: A study was conducted on 167 subjects including both males and females. The ear was measured using vernier caliper with an accuracy of 0.001 and recorded in millimeters (mm) in a data sheet. The size of pinna and the lobule were measured on both right and left side and were correlated with age of the individual. Readings were statistically analyzed in order to determine the relationship between the size of the pinna and the age of the individual. Results: In our study of age 18-30 ear length was 6.15 cm, lobule length and width was 1.87 cm and 1.99 cm and in age 31-40 ear length was 6.32 mm, lobular length and width was 1.95 cm and 2.01 cm and in age 41-50 yrs ear length was 6.415 cm, lobular length and width was 1.98 cm and 2.06 cm. This shows that in our study ear length were increasing significantly with age and similarly Rt and Lt lobular length and Lt lobular width were also increasing significantly with the age. There was no significant difference between the size of the right and left pinna. Conclusion: The present study shows that the expansion of auricle with age was related to structural change in auricular cartilage. The ear morphometry also helps in predicting ear anomalies and to reproduce anatomically corrected ear during its reconstruction.