This study aims to determine whether the Ethanol Extract of Jackfruit Leaves has antibacterial properties and to determine the concentration of Ethanol Extract of Jackfruit Leaves which is useful as an antibacterial to the growth of Staphylococcus aureus bacteria. The samples tested in this study were young jackfruit leaves (not too young). Fresh jackfruit leaves weighed 1000 g, dried jackfruit leaves, 386.06 g and mashed jackfruit leaves 232.12 g and weighed 200 g. The results of research conducted from testing Ethanol Extract of Jackfruit Leaves on the growth of Staphylococcus aureus bacteria can be concluded that: Ethanol Extract of Jackfruit Leaf (Artocarpus heterophyullus L) has an antibacterial effect on the growth of Staphylococcus aureus bacteria at 50% concentration.
Red ginger (Zingiber officinale) contains many chemical compounds that have many activities. This study aims to determine the active compounds of Zingiber officinale and immunomodulatory activity that can increase the phagocytosis of macrophage cells and lymphocyte cell proliferation. Red ginger extract compounds were identified using GC-MS. The parameters of immunostimulatory activity were macrophage phagocytosis and lymphocyte proliferation, the preparations were made in several extract concentrations. This research is an experimental study in the laboratory. The research included fresh red ginger, made into ethanol extract, dried. The results were made a suspension, the extract was then given to macrophage cells (phagocytosis testing) and lymphocyte cells (proliferation testing) in vitro to test the immunomodulatory effect. The results showed that the most active extract in macrophage phagocytosis activity was the extract concentration of 500 ppm. While the activity of lymphocyte proliferation was shown by the concentration of group A (Cell, 500 ppm extract, MK, Engerik). The active compound contained in the ethanol extract of red ginger is thought to be Geraniol
Salah satu penyebab infeksi adalah bakteri Staphylococcus aureus. Antibakteri telah memberikan kontribusiyang efektif terhadap kontrol infeksi Staphylococcus aureus. Salah satu tanaman tradisional yang dianggapmemiliki khasiat antibakteri adalah daun sirsak (Annona muricata L.). Tujuan dari penelitian ini untukmengetahui efektivitas rebusan daun sirsak (Annona muricata L.) sebagai antibakteri terhadap bakteriStaphylococcus aureus. Bakteri adalah sel prokariotik dan uniselular. Bakteri Staphylococcus aureusmerupakan salah satu bakteri gram positif dan dapat menyebabkan penyakit diare,nyeri otot, dan penyakitkulit seperti jerawat, borok dan bisul. Penelitian dilakukan dengan metode eksperimental secara ujimikrobiologi dengan pengambilan sampel secara purposive sampling. Sampel penelitian adalah daun sirsak(Annona muricata L.) yang diambil dari daerah Perumnas Mandala - Medan. Uji aktivitas antibakteridilakukan menggunakan metode difusi yaitu menggunakan media agar yang telah ditanami bakteri,kemudian dibuat 5 hole. Empat hole ditetesi larutan uji yaitu rebusan daun sirsak 10%, 20%, 30%, 40% dansatu hole ditetesi kontrol negatif yaitu aquadest. Menurut Farmakope Indonesia Edisi IV, zona hambatanantibakteri yang memuaskan adalah 14-16 mm. Dari data hasil pengamatan dapat dilihat bahwa rebusan daunsirsak 10% dan 20% belum dapat dikatakan sebagai antibakteri, tetapi sudah dapat menghambatpertumbuhan bakteri. Rebusan daun sirsak 30% dan 40% telah dapat dikatakan sebagai antibakteri denganmasing-masing diameter zona hambatnya 14,8 mm dan 18,5 mm. Kontrol negatif yaitu aquadest ternyatatidak memiliki efek antibakteri
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