The aim of present study was to investigate and compare indole metabolites of fruit bodies, mycelium cultivated <i>in vitro</i> and culture medium of the fungus <i>Aleuria aurantia</i> (Fr.) Fuck. By use of a number of chromatographic and spectroscopic methods several indole metabolites have been detected and identified among other the 3-indolebutyric acid was produced and extracted to the culture medium. Furthermore 3-indoleatonitrile and tryptophane degradative products have been found both in fruit bodies and mycelium.
Aromatase is a cytochrome P-450 enzyme responsible for the conversion of the androgens, androstenedione, and testosterone, to the corresponding estrogens, estrone, and estradiol, respectively. Several flavanoids have been shown to be inhibitors of aromatase (1), and we and others have de-
Subject to analysis was mycelial culture of <i>Xerocomus chrysenteron</i> and its metabolites which night be of pharmaceutical on toxicological interest. Several groups of metabolites were analysed: steroids, fatty acids, indole desiratives, aminoacid, sugars - using chromatographic analytical methods. Amony others soma interesting idolic substances were detected.
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