Aromatase is a cytochrome P-450 enzyme responsible for the conversion of the androgens, androstenedione, and testosterone, to the corresponding estrogens, estrone, and estradiol, respectively. Several flavanoids have been shown to be inhibitors of aromatase (1), and we and others have de-
The aim of present study was to investigate and compare indole metabolites of fruit bodies, mycelium cultivated <i>in vitro</i> and culture medium of the fungus <i>Aleuria aurantia</i> (Fr.) Fuck. By use of a number of chromatographic and spectroscopic methods several indole metabolites have been detected and identified among other the 3-indolebutyric acid was produced and extracted to the culture medium. Furthermore 3-indoleatonitrile and tryptophane degradative products have been found both in fruit bodies and mycelium.
Subject to analysis was mycelial culture of <i>Xerocomus chrysenteron</i> and its metabolites which night be of pharmaceutical on toxicological interest. Several groups of metabolites were analysed: steroids, fatty acids, indole desiratives, aminoacid, sugars - using chromatographic analytical methods. Amony others soma interesting idolic substances were detected.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.