The influence of pollen extracts (Cernitin GBX and Cernitin T60) on some allergic reactions in animals and on the degranulation of mast cells and liberation of histamine has been studied. It was found that the cernitins possess antiallergic properties in uiuo and in uitro. Both pollen preparations were able to inhibit the degranulation of mastocytes and histamine release from these cells. The results indicate that antiallergic properties of the cernitins might be dependent on their interaction with the mastocyte.
G′? Die Amide (I)‐(III) wurden durch Umsetzung entsprechender Säurechloride mit Cyclohexylamin, das Bisamin (IV) durch Reaktion von Cyclohexylamin mit 1,3‐Dibrom‐propan erhalten.
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