The media play an important role in the dissemination of information on the 2019 novel coronavirus disease (COVID-19) pandemic. However, it is important to measure whether the population is receiving information that calms it down, as well as whether such news are in accordance with the magnitude of the issue. Objective: To validate a questionnaire that measures the perception of the media and their informative role in the face of COVID-19 pandemic. Methods: A validation process for a questionnaire that measures the perception of the magnitude of this issue and whether it generates fear was carried out. The validation was performed by means of a literature search. Moreover, a first version of the scale was developed, which was assessed by 30 experts (physicians, epidemiologists, among others). After this, an exploratory factor analysis and descriptive statistics were performed. Results: Our scale had 13 initial items; however, one of them was eliminated because of its unsatisfactory level of statistical adequacy. Exploratory factorial analysis and parallel analysis suggested three factors. Results of the KMO coefficient (0.833) and the Bartlett's test of sphericity (4998.5; gl = 66; p<0.001) were acceptable and significant, which justify the exploratory factorial analysis. The correlation between the factors was >0.4 and robust analyses revealed a satisfactory factorial structure (X2=88.0; p= 0.001; IFC=0.968; GFI=0.992; TLI=0.937; RMSEA=0.123). In the descriptive statistics of the 12 final items, moderate and significant correlations between the items were reported (> 0.5). Conclusion: We generate a scale to validate the perception of how people receive information from the media. Thus, this scale can be used to measure the informative role of the media regarding the COVID-19 pandemic, and may even serve for other similar public health emergencies.

Early neonatal sudden death syndrome (SIDS) is a rare but well known disease entity. Between January 1975 and December 1991, 29 full-term newborn infants delivered in our maternity unit and, considered healthy at birth, suffered early SIDS (n = 15) or early apparent life threatening events (ALTE) (n = 14). Data from the whole population of live full-term infants born in our hospital during the past five years have been used as a reference (n = 27,841). The general rate of early SIDS was 0.14 per 1000 (15/107,263). Combining early ALTE cases, the overall rate was 0.27 per 1000 (29/107,263). A postmortem examination was performed for all infants who died (20/29): no cause of death could be determined, and we did not observe a single case with evident sequelae. There were 9 deaths (31%) within the first hour after delivery and 12 deaths occurred in the early morning hours (04:00-08:00; RR = 3.76; p = 0.0008). The lowest incidence was in the spring (RR = 0.21; p = 0.03). There was a tendency for an increased incidence during the weekend and the summer. No influence of sex, maternal age, gestational age, infant weight presentation, delivery, anesthesia or presence of meconium-stained fluid was found. In our opinion, SIDS can take place even during the first hour of life and it is not possible to predict when a baby might be affected. Pediatrically trained caregivers, close observation by the mother during the first few days and resuscitation facilities in maternity wards may be the most important preventive measures to reduce the risk of early SIDS and the consequences of ALTE in the early newborn period.

Since the announcement of the start of SARS-CoV-2 vaccines development, many myths and vaccine opponents have come to the fore. Therefore, in this scenario, it is imperative to have an instrument to assess the population perception of this subject matter.Objective: To validate a scale to measure the perception of SARS-CoV-2 vaccines acceptance.Methods: This is an instrumental and multicentre study, through which a list of possible reasons for whether or not people would be vaccinated was generated. After submitting them to 15 experts, a pilot survey was conducted virtually in a population of almost 3000 participants in the 24 regions of Peru. Descriptive statistics and the exploratory factor analysis (EFA) were conducted using the FACTOR program. Results:The Kaiser-Meyer-Olkin (KMO) coefficient (KMO = 0.917) and the Bartlett's test of sphericity (3343.3; gl = 136; p < 0.001) were conducted. According to EFA results, two factors were found to explain 58.17% of the total variance. The fit indices show that the proposed model is adequate (χ 2 = 826.321; df = 43; p = 0.001; RMR = 0.054; GFI = 0.952; AGFI = 0.927; CFI = 0.946; TLI = 0.931; and RMSEA = 0.078). Finally, Cronbach's α was found to be very satisfactory for the generated scale (α = 0.831; 95% CI = 0.82 -0.84). Conclusion:A simple and efficient scale was validated to assess positive and negative perceptions of SARS-CoV-2 vaccines (the VAC-COVID-19 scale), with a Cronbach's coefficient of 0.831.

Fear is a natural response to something unknown. In the current scenario, it is important to assess it in relation to the coronavirus disease-19 (COVID-19) pandemic in Latin American countries. Objective: To determine the fear perception according to factors associated with the COVID-19 pandemic in Peru. Methods: An analytical cross-sectional study was conducted based on a virtual questionnaire. The main question was "how much fear people had of COVID-19?", using a scale from zero (without fear) to 10 (very fear). This scale was divided into tertiles, and the upper tertile was the reference category (compared to the middle and lower tertiles). Statistical significances between fear perception of COVID-19 and sociodemographic data were calculated. Results: A total of 3887 participants responded the questionnaire about fear perception. In the multivariate analysis was found that women (adjusted prevalence ratio (

Plasma fatty acids were studied in 20 full-term newborn infants fed human milk and in 17 newborn infants of identical characteristics fed an adapted cow's milk formula. Plasma fatty acids were measured in cord blood and at 7-9 days of age. No differences were present at birth but, after a period of feeding, infants receiving breast milk had higher plasma concentrations of stearic acid, di-homo-gamma-linolenic acid and arachidonic acid, while infants receiving formula had a higher plasma concentration of oleic acid. The importance of these findings in relation to the lipidic structure of the nervous system remains to be determined.

Total plasma fatty acids were analysed in 75 first trimester pregnant women, 32 second trimester pregnant women, 27 women at delivery and 38 non-pregnant women. Eleven fatty acids were studied by capillar gas chromatography SP-column. Compared with non-pregnant women, in the first trimester there was a significant percentual increase in palmitic, palmitoleic, stearic and docosahexaenoic acids, whereas linoleic and eicosapentaenoic percentually decreased. Between the first and second trimester a significant increase in the proportion of palmitic acid and a significant percentual decrease in arachidonic acid was detected. Between the second trimester and delivery the aforementioned changes were more marked. Between the second trimester and delivery there was also a significant percentual increase in oleic and linolenic acids, whereas the proportions of stearic, linoleic, dihomogammalinolenic and docosahexaenoic acids significantly decreased. It is suggested that the intake in polyunsaturated fatty acids should be increased during pregnancy, specially in the third trimester.

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A successful pregnancy with a normal baby in a woman with acute promyelocytic leukemia treated with daunorubicin from the ninth week of gestation is reported. Daunorubicin is an effective agent against this leukemia during pregnancy. That daunorubicin may be safely used, when required during the early gestation, is suggested.