The treatment of relapsing chronic infections (RCI) encounters many difficulties. In the present study, the use of the immuno adjuvant P40 either alone or in association with vaccinotherapy for the treatment of RCI turned out to be very effective, whereas vaccinotherapy alone was not. It is hypothesized that cell-mediated immunity may play a major role in controlling RCI, since the clinical improvement of the patients kept up with the positivation of previously negative skin tests carried out with either the specific infecting agent or with recall-anti gens.
RésuméQuarante-six souches de Dermatophytes ont été isolées à par tir de quatre-vingt-dix-neuf Rongeurs capturés dans l'Est de la France. Elles appartenaient aux espèces Trichophyton mentagro phytes, Trichophyton terrestre et Microsporum persicolor. La forme parfaite de cette dernière espèce, Nannizia persicolor, a été obtenue.L'étude de la répartition des Dermatophytes chez les Rongeurs parasités montre une relation entre l'espèce fungique et l'espèce du Rongeur, mais aucune influence du biotope de capture de l'hôte. Il est possible que ce résultat soit dû à la relative homo généité du milieu étudié.
SummaryForty-six strains of Dermatophytes were isolated from ninety nine Rodents captured in the East of France.They belonged to the following species : Trichophyton menta grophytes, T. terrestre and Microsporum persicolor. The sexual form of this last species, Nannizia persicolor, was obtained.
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