SKELETAL CHANGES OF THE AMPUTATION STUMP AND THE FEMUR ON THE AMPUTATED SIDE A Clinical Investigation J. A. SEVASTIKOGLOU, U. ERIKSON & S.-E. LARSSON Weccived 27.iii.68 This investigation has been aided by grants from the Swedish State Medical Research Council (Contracts Nos. Y. 171 and B. 66-214).

No abstract

The vital capacity (VC) and the maximal voluntary ventilation (MVV) were studied in 29 patients with scoliosis (predominantly idiopathic). The results obtained confirmed earlier observations that scoliotic patients have decreased VC and MVV. The immediate effect of the application of the Milwaukee brace was a slight though statistically significant decrease in MV, whereas there was no significant effect on VC. Treatment with the Milwaukee brace for a mean period of 15 months did not appreciably influence the VC or MVV, as a percentage of the predicted normal values of the patients, when measured without the brace applied.

SUMMARY The immediate effect of lα‐hydroxyvitamin D3 (1α‐OHD3) and calcium on blood and urine chemistry and intestinal calcium absorption rate was studied in seventeen patients, six with sede, five with post‐menopausal, and six with corticosteroid‐induced osteoporosis. In all groups, there was a significant increase in calcium absorption rate and uripary calcium excretion. In patients with post‐menopausal and corticosteroid‐induced osteoporosis, the serum calcium level was significantly increased even further. In patients with corticosteroid‐induced osteoporosis, the excretion of urinary phosphate increased significantly. In the other groups, it also increased, although non‐significantly. The effect of long‐term treatment with 1α‐OHD3 and calcium supplements was followed in five patients with senile and five with post‐menopausal osteoporosis. Six patients were fully relieved from lumbar pain, and, in nine, physical activity was greatly improved. Despite the treatment, compression of lumbar vertebrae increased in three patients. In both groups, urinary calcium excretion increased significantly. Six patients had occasional hypercalcaemia, although their serum calcium and phosphate were generally normal. The uripary phosphate excretion decreased, although non‐significantly. The bone mineral content rose in five patients and decreased in another five, although non‐significantly. The trabecular bone area determined by repeated bone biopsies in four treated patients significantly increased.

No abstract

No abstract

No abstract

No abstract