During the last few years there has been a trend in myocardial revascularization of older patients, with more coexisting disease. Despite the fact that hospital mortality seems stable, there is an increase in major postoperative morbidity.

No abstract

IgM and IgG antibodies to Mycoplasma pneumoniae were measured in 147 sera from four groups of patients by means of an indirect enzyme-linked immunosorbent assay (ELISA) and the results compared with those obtained by other methods. A good correlation was demonstrated between the complement fixation test and ELISA-IgM and to a lesser extent ELISA-IgG; for the metabolic inhibition test the reverse was the case. The indirect haemagglutination test appeared to detect mainly IgM antibodies. Low levels of IgM antibodies were detected by ELISA in 60 sera of children not suffering from pneumonia. However, if only high titres (greater than 800) were regarded as indicative of Mycoplasma pneumoniae infection, a presumptive diagnosis could have been made in 42 of 73 single acute phase sera from patients. Comparable results were obtained with IHA. The diagnostic level of IgM antibodies. was reached during the second week of the disease. It is concluded that examination of a single serum sample by either ELISA-IgM or IHA may assist in early diagnosis of Mycoplasma pneumoniae infection.

No abstract

Reoperation, nephrological and pulmonary problems are strong predictors, obesity and age independent preoperative risk factors for sternal wound complications.

No abstract

This study is motivated by the time lag between date of diagnosis of AIDS cases and date of reporting, which results in incomplete data about the epidemic. A maximum likelihood procedure has been developed to adjust the actual numbers of diagnosed AIDS cases for reporting delay. If a parametric function for describing past and future incidence is assumed, its parameters and the adjustment for reporting delay can be estimated simultaneously. Data from the WHO Collaborating Centre on AIDS, Paris, are used. Practical problems related to data collection are dealt with.

Peripheral vascular atherosclerosis, neurological pathology, aorta-pathology, the occurrence of a perioperative myocardial infarction and the time cohort 1993-1995 are identified as independent risk factors for neurological complications.