Periodontitis is a common complication in patients with diabetes. Their classification is complex and it is based on the clinical presentation

Background and Aim: Skin autofluorescence (AF) is a method used to detect the accumulation of Advanced Glycation End Products (AGEs)

Introduction.Hepatic steatosis is a reversible condition caused by accumulation of triglycerides in liver cells. Non-alcoholic fatty liver disease (NAFLD) can progress to advanced liver disease: fibrosis, cirrhosis, liver failure, cancer, and finally can lead to death; therefore NAFLD contributes significantly to morbidity and mortality of hepatic cause. Materials and methods: The study was conducted on a group of 88 patients with Body Mass Index (BMI) ≥ 30kg/m², they were excluded patients with known diabetes. Results, Discussion: The statistical analysis showed that in more than half of subjects elastometry values were higher than those considered normal, obesity is a risk factor for NAFLD that progresses in hepatic fibrosis. Conclusions: Liver fibrosis is present in high percentage in patients with obesity (52% of subjects) and it was positively correlated with age, arterial stiffness and fasting glucose. key words: steatosis, fibrosis, obesity.

Cardiac failure (CHF), renal disease and anemia are interconnected in the Cardio-Renal Anemia syndrome. Diabetes mellitus remains the most common cause of endstage renal disease (ESRD) in the developed world and when it is associated with these three conditions it worsens the outcomes of these patients. Aim: to evaluate renal anemia and cardiac dysfunction in patients with chronic kidney disease with and without diabetes mellitus (DM). Materials and methodswe assessed 100 patients (40 women and 60 men), 41 patients with DM and 59 patients without DM. All patients had Chronic Kidney Disease (CKD) -estimated glomerular filtration rate (eGFR) under 60 ml/min/1,73 mp. We considered anemia when the value of haemoglobin (Hb) was under 11 g/dl. Results -Mean age of the studied patients was 60.38±11.79 years old in women and 59.28±13.89 years old in men. The prevalence of anemia was high in diabetic and non-diabetic patients, too. Anemia was more severe in patients with cardiac dysfunction than in those with normal cardiac function. The higher prevalence of cardiac dysfunction was in patients which had both anemia and DM. There were no significant differences about prevalence of diastolic or systolic cardiac dysfunction in non-diabetic versus diabetic patients. Conclusions -Anemia was an independent predictor for the development of cardiac dysfunction in patients with CKD and the prevalence of cardiac dysfunction was higher in patients who had both anemia and DM than in those without anemia and DM.

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