(−)‐4a,5‐Dihydrostreptazolin has been synthesized in nine steps from D‐glyceraldehyde acetonide. Key steps include a diastereoselective addition of a vinylic Grignard reagent to an imine derived from D‐glyceraldehyde acetonide, a ring‐closing metathesis, and a stereoselective radical‐mediated enyne cyclization.
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