BACKGROUND:Nowadays, successful treatment of cancer is not only measured by 5-years survival rate, but also by the patient’s quality of life (QOL). Delayed in the seeking of cancer treatment resulted in high morbidity and impact on the quality of life.AIM:This study aims to assess the QOL of patients with gynecologic cancer after therapy. The results of this research can be used as a basis for cancer treatment that should be holistic, not only to eradicate the disease, but also improve QOL.METHODS:A total of 47 respondents who went to the Department of Oncology, Haji Adam Malik Hospital Medan from May to October 2015 were asked to fill out the FACT-G questionnaire for the QOL assessment. The patient’s personal and disease data was taken from the medical records. The data were analysed statistically by one-way ANOVA test.RESULTS:The results showed that the physical, social, emotional and functional of cancer patients were not much different based on the variables studied. The QOL was higher in patients with endometrial cancer compared with other types of cancer. The QOL was also higher in patients who had completed treatment (> 6 months) and early-stages cancer. There was no statistical difference between the QOL of patients with gynecologic cancer based on therapeutic modalities, duration of treatment and the stage of disease (p > 0.05).CONCLUSION:This current study found the QOL, physical, and emotional complaints are still encountered.
Placenta accreta is considered a life-threatening condition and is a cause of maternal death. Placenta accreta causes 7% -10% of cases of maternal mortality worldwide. Previous Sectio Ceasarea (SC) and uterine surgery are the most common risk factors for placenta accreta. Placenta accreta occurs when villous placenta invades directly into the myometrium. The incidence of placenta accreta increases with increasing incidence of SC. this wa is descriptive with a retrospective study. From 2016 – July 2019 there were 59 cases of placenta accrete with an increase in the number each year. Risk factor for the history of sectio ceasarea (94,8%). Sectio ceasarea + hysterectomy is a procedure of placenta accreta. There were no maternal mortality from 2016 – 2019 up to July. The annual incidence of placenta accreta increases each years mean risk factors dominant placenta accreta is history sectio ceasarea.
BACKGROUND: Long-term sequelae of cesarean section (CS) is formation of niche in CS surgical scar. Blood glucose involved in wound healing process after CS. AIM: This study was to find correlation of blood glucose level with niche in CS patients. METHODS: This research was an observational and analytic study with case series design conducted at Department of Obstetrics and Gynecology, Universitas Sumatera Utara, RSUP H Adam Malik Medan, and Sundari Hospital Medan Starting from July to August 2022. To assess correlation between variables, eta test was used to assess the correlation of blood glucose with incidence of niche. The analysis results were said to be significant if p < 0.05, with 95% CI. RESULTS: Mean of patients were in 21–29 years (70%), multiparity with 12 patients (40%), aterm gestational age with 30 patients (100%), 16 patients (53.3%) with anteflexion uterus, previous CS 2 times were the majority with 9 patients (30%), and 17 patients (56.7%) were elective CS. Incidence of niche was 63.3%. Triangular were the most found niche with 11 patients (36.7%). Mean of total myometrial thickness, depth of niche, and residual myometrial thickness were 5.23 ± 11.2 mm, 2.44 ± 2.75 mm, and 5.23 ± 11.22 mm, respectively. Mean blood sugar level was 103.3 ± 17.4 mg/dl. From eta analysis, there was no correlation between blood glucose levels post-CS patients using eta test with p = 0.872. CONCLUSION: There was no significant correlation between blood glucose levels on niche incidence in post-CS patients.
Background : Ovarian cancer is one of women death causes and almost diagnosed at advanced stage which related to high recurrence rate therefore accurate biomarker is needed to predict recurrence rate. Aim: This research purpose to determine correlation of fibroblast activation protein (FAP) expression and epithelial ovarian cancer recurrence at H. Adam Malik Hospital Medan. Methods: This research is an analytic observational study with case control approach that will be carried out starting in May 2022 until number of samples is met. Immunohistochemical assessment for FAP expression uses Allred score because this system is simplest and has good sensitivity and specificity. The preparations were interpreted by two anatomical pathologists. The correlation between variables was carried out by chi square statistical test with 95% confidence interval and p < 0.05 was considered significant. Results: The analysis results using Chi Square test showed that there was a significant relationship between tissue FAP expression and ovarian cancer recurrence (p = 0.004). The OR value obtained was 7.429 (95% CI = 1.778 – 31.040), which means patients with tissue FAP expression (+) had risk of recurrent ovarian cancer 7.429 times greater than patients with tissue FAP expression (-). Conclusion : There is a statistically significant correlation between FAP expression and epithelial ovarian cancer recurrence.
HIGHLIGHTS 1. COVID-19 raises concern in regard with its effect on pregnancy.2. The serological descriptions of umbilical cord of neonates born from mothers suffering from COVID-19 were identified.3. Most of the serology was non-reactive IgG and IgM, followed was reactive IgG and the least was the reactive IgM. ABSTRACT Objective: To evaluate the serological description of the neonatal umbilical cord in COVID-19 mothers confirmed by RT-PCR at Rumah Sakit Umum Pusat (RSUP) H. Adam Malik Medan in January-June 2021. Materials and Methods: This study was an observational study with a case series approach where the cases were mothers infected with SARS CoV-2 confirmed by RT-PCR. The study was conducted at Universitas Sumatera Utara (USU) Hospital Laboratory and RSUP H. Adam Malik for 6 months, from January 2021 to June 2021. The data collected were analyzed using descriptive statistics. If the data were normally distributed, they were presented as mean + SD; otherwise, they were presented as median (min-max) for each variable. The Statistical Package for Social Sciences version 22.0 (IBM SPSS Corp.; Armonk, NY, USA) was used for statistical analysis. Results: Neonatal umbilical cord serology results (IgM and IgG) were predominantly non-reactive, where IgM was non-reactive in 43 neonates (97.7%) and IgG was non-reactive in 37 neonates (84.1%). In mothers without COVID-19 symptoms, neonate umbilical cord serology results were dominated by non-reactive IgM (88.6%) and IgG (79.5%). In mothers who recovered from COVID-19, neonate umbilical cord serology results were also dominated by non-reactive IgM (95.5%) and IgG (81.8%). Conclusion: The neonatal umbilical cord serology results from the mother confirmed with positive COVID-19 were nonreactive IgG and IgM in the majority of 35 (79%) samples, reactive IgG in 7 (15.9%), and reactive IgM in 1 (2%) sample.
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