There is presented the structure of acute intestinal infections (AIIs) at the outpatient stage of medical care in 135 outpatients (70 men and 65 women, aged from 15 to 55 years) visited the Health Center of Barnaul. In all patients, the mild course of gastroenteritis predominated (the stool frequency did not exceed 4-5 times a day, body temperature - 37.2 0C). The investigation of biological material from patients (feces) was carried out by polymerase chain reaction (PCR) with hybridization-fluorescent detection “AmpliSens® AII screen-FL”. The results showed the high efficiency of the test system used, as in 118 out of 135 samples (87%) there was found genetic material of different etiology, 66.1% were of the viral origin, among which rotaviruses and noroviruses prevailed, 25.4% of samples had bacterial origin (Salmonella prevailed) and 19.5% of mixed virus-viral or bacterial-viral etiology. The work showed both the high sensitivity and specificity of the PCR method in the etiological diagnosis of AII. Among the examined patients, AII of viral origin prevailed (66.1%).

Food products contamination with xenobiotics of various genesis exerts negative influence on population health. According to multiple research performed on various territories in Russia, nitrates are basic contaminants occurring in food products and they make a considerable contribution into higher morbidity with specific nosologic forms, notably pathologies which are primarily caused by factors related to nutrition.The paper focuses on analysis of laboratory research data on nitrates concentrations in food products; the data were collected in Altai region and they are taken from research reports issued by certified test laboratories. The authors also performed their own laboratory research at the Institute for Occupational Hygiene and Industrial Ecology of the RF Public Healthcare Ministry; it allowed to conclude that increased nitrates contents in food products were a vital issue which requires further examination and research performed with high precision laboratory research techniques.We assessed hazard quotients (HQ) for nitrates occurring in vegetables and melons, individual carcinogenic risks (ICR), and population carcinogenic risks (PCR). Our hygienic assessment of nitrates concentrations in food products allowed us to reveal boundaries of risk properties variability.It is necessary to work out recommendations how to reduce exposure of Altai region population to nitrates and to give grounds for priority approaches to administrative decision-making aimed at lowering population risks caused by consumption of nitrates-contaminated food products.

The study assessed the physical development of rural and urban children aged of 7-10 years in the Altai Territory for somatometric and physiometric indices (height, body weight, chest circumference, vital capacity of lungs, dynamometry, arterial pressure). Somatometric indices of the physical development in rural children of primary school level have been established to be statistically significantly higher than similar indices of urban children in boys and girls. The evaluation of physiometric indices in groups of rural and urban children revealed another trend. Indices of the right-hand muscle strength, the vital capacity of lungs, arterial pressure (systolic and diastolic) by 10 years in urban children begins to exceed these indices of rural peers. The revealed differences in the physical development of rural and urban children show a different combination and a share of the influence of environmental factors on the schoolchildren’s organism.

We performed morphological analysis of the effect of the peptide complex from porcine kidneys on the course of experimental urolithiasis modeled in rats by treatment with 1% ethylene glycol solution (in drinking water) for 6 weeks. The peptide complex obtained by acetic acid extraction was administered in a dose of 15 mg. Administration of the peptide complex to animals with experimental kidney stone disease leads to 100% destruction of large and medium stones to the "dust" granularity.