Assessment of risks caused by impacts exerted on a human body by nitrates contained in food products

Saldan, I.P.; Shved, O.I.; Balandovich, B.A.; Nagornyak, A.S.; Mazko, O.N.; Makarova, O G; Filippova, S.P.; Zhukova, O.V.; Potseluev, N.Yu.

doi:10.21668/health.risk/2018.4.09.eng

Cited by 4 publications

(5 citation statements)

References 5 publications

(10 reference statements)

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“…According to recent studies, the average values for the content of this component in food raw materials, for example, for the Siberian region, is 262 mg/kg of raw materials in total for different groups of vegetables and fruits. In this publication, we provide calculated values for nitrate intake of 170 mg/day/1 person [ 30 ], which is confirmed with values in other published studies [ 31 , 32 ]. At the same time, it is known that, for example, boiling can reduce, on average by ≈12.2%, the values of the nitrate concentration in the processed raw materials, while frying, on the contrary, increases the proportion of residual nitrates [ 33 ].…”

Section: Methodssupporting

confidence: 84%

“…It ranges from 0.26 to 8.08 mg/kg of products. We also take into account the mass of incoming nitrates in 170 mg/kg of raw materials [ 30 ], but we will take a lower value as if all food products were cooked by boiling (−12.2% nitrates) [ 33 ]. Taking into account the fact that vegetables and fruits account for approximately 25% of the total diet (we summarize pesticides separately, since they can also be found in animal products), we calculate the final value, which ranges from 37.6 to 45.4 mg/kg of food consumed.…”

Section: Resultsmentioning

confidence: 99%

“…In addition to pesticides, we will take into account such components of food systems as nitrates, which can also contribute to malignancy of gastrointestinal cells [ 30 ]. According to recent studies, the average values for the content of this component in food raw materials, for example, for the Siberian region, is 262 mg/kg of raw materials in total for different groups of vegetables and fruits.…”

Section: Methodsmentioning

confidence: 99%

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Estimating the Mass of Food Components Necessary for the Utilization of Free Radical Particles in the Human Body

Gorbachev

Nikulchev

Kosenkov

et al. 2022

IJERPH

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The article proposes an algorithm for an approximate assessment of the molar volume of free radicals generated in the human body per day. It takes into account the act of breathing, physical activity, food consumption, the influence of unfavorable environmental conditions, exposure to xenobiotics, as well as bad habits (alcohol and tobacco smoking). A calculation of the required set of the most commonly used food products for the disposal of free radicals was made. The calculation is a structure of four blocks with the possibility of adding optional data from human population genetic studies, environmental conditions, etc. In the proposed algorithm, the results of antiradical activity (ARA) of food products are used as input, including the results of predicting antiradical activity using artificial neural networks (ANN), which we published earlier. Based on the accepted values of one equivalent (in terms of the activity of 1 μmol of ascorbic acid), it was shown (for our data) that for the utilization of all free radicals produced in the human body per day, it will take an average of ≈260 to ≈540 g of food components in terms of dry mass (including proteins, fats, carbohydrates, etc.). At the same time, for the utilization of consumed xenobiotics, from 220 mg (in terms of vitamin C) to 260 mg (in terms of acetylcysteine -NAC ) of additional plastic components or 11.5–13.0 g of essential amino acids will be required, which must be taken into account when calculating diets. This approach will be useful in the development of new functional foods, as well as in assessing the possible impact of diets on human health. Another applied point of this study is related to the possibility of using these data for better detailing and selection of food products for people working in conditions of increased radiation (in space conditions), in contact with harmful substances (chemical synthesis and production), for people practicing increased physical activity (bodybuilding and sports), and for the purposes of medical nutritional therapy.

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Section: Methodssupporting

confidence: 84%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Estimating the Mass of Food Components Necessary for the Utilization of Free Radical Particles in the Human Body

Gorbachev

Nikulchev

Kosenkov

et al. 2022

IJERPH

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“…In Baikalia region samples, taken from major VPs, the nitrate content was, on average, 268±45.2 mg/kg in cabbage and 84±11.6 mg/kg in potatoes. The diet of Baikalia residents differs significantly from food preferences of the population in the southern regions of the Russian Federation [3,13,14] and other countries [10,19,20]. Therefore, chemical and analytical research focuses on the VP types commonly used by the local population.…”

Section: Discussionmentioning

confidence: 99%

“…Results of numerous publications, including those by Lin Y.J., et al, implied an absence of significant risks from the effects of nitrates and nitrites in vegetables for most population groups, but at the same time, preschoolers constitute a very sensitive group [10][11][12]. Despite a large number of studies on the problems of VP quality and safety, there are still limited data on the formation of health risks for the population of Siberian regions caused by the influence of foods and produce contaminated with nitrates [13,14]. Such comparative study identifying territories and risk groups for the development of preventive recommendations is of substantial interest.…”

Section: Introductionmentioning

confidence: 99%

Contamination Of Vegetable Products With Nitrates As A Public Health Risk Factor

2021

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Our study aimed to investigate the contamination levels of vegetable products with nitrates and to evaluate the associated health risks to population of Baikalia. Materials and Methods — The characterization of VP contamination with nitrates is based on the data of the Federal Information Foundation for Public Hygiene Monitoring in the Russian Federation for 2015-2019. The computation of hazard ratios was conducted sensu the Guidelines 2.1.10.1920-04 ‘Human Health Risk Assessment Caused by Environmental Pollutants’. Results — The proportion of VP samples with augmented nitrate content in the Republic of Buryatia was 4.5 times higher than in Irkutsk Oblast. At the same time, nitrate concentrations did not differ significantly: in the Republic of Buryatia, median concentration was 164.24 (158.52–169.95) mg/kg, and 90th percentile was 940.76 (868.49–1013.03) mg/kg; in Irkutsk Oblast, corresponding amounts were 169.1 (158.55–177.55) and 978.0 (927.3–1028.7) mg/kg (p>0.05). The alimentary effect of nitrates on the child population in Republic of Buryatia led to unacceptable risk (HQ>1.0 at the level of the average centile trend). Conclusion — The results of conducted analysis confirmed the need to carry out dynamic studies of child health indicators due to the impact of nitrates in the municipalities of the cluster 1 in the course of the public hygiene monitoring (with child health as a mandatory component of the latter) for developing further predictive indicators.

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Comparative Assessment of Nitrate Concentrations in Vegetables Grown on Commercial and Subsistence Farms in the Saratov Region

Елисеев¹,

Чехомов²,

Елисеева³

2021

PH&LE

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Background: Food safety is one of the prerequisites for a healthy diet of the population of the Russian Federation. At the same time, successful functioning of modern agricultural complexes is almost impossible without a widespread use of various agrochemicals, including nitrogen-containing fertilizers. The objective of our study was to conduct a comparative assessment of the nitrate content of vegetables grown on commercial and subsistence farms located in industrially contaminated areas of the region and used as local food. Materials and methods: The research was carried out in the summer and autumn periods of 2017–2019 in a number of polluted areas of the Saratov Region. Nitrate concentrations in local vegetables were measured by a potentiometric method. Results: We established that the nitrate content of vegetables grown in most environmentally disadvantaged areas varied greatly. Concentrations of this contaminant depended on the type of vegetables, growing conditions and region; yet, they did not exceed the maximum permissible level in any vegetable sample tested. At the same time, the level of nitrates in crops grown on commercial farms was significantly higher than that in vegetables grown in private gardens (p < 0.05) due to a more extensive application of nitrate fertilizers in the form of commercially produced ammonium nitrate. Private gardeners, on the opposite, use biomass species, usually legumes, contributing to a better conversion of nitrates into proteins and preventing their excessive accumulation in the produce.

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Assessment of risks caused by impacts exerted on a human body by nitrates contained in food products

Cited by 4 publications

References 5 publications

Estimating the Mass of Food Components Necessary for the Utilization of Free Radical Particles in the Human Body

Estimating the Mass of Food Components Necessary for the Utilization of Free Radical Particles in the Human Body

Contamination Of Vegetable Products With Nitrates As A Public Health Risk Factor

Comparative Assessment of Nitrate Concentrations in Vegetables Grown on Commercial and Subsistence Farms in the Saratov Region

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