No abstract

Persistent perineal sinus is more likely to occur if an extrasphincteric dissection is needed because of extensive anorectal disease or if fecal contamination occurs at operation. Attempted surgical eradication of perineal sinus is often ineffective.

Increased cytokine expression occurs in both active UC and pouchitis and to a lesser extent in the long-standing ileoanal pouch.

Strictureplasty for duodenal Crohn's disease is associated with a high incidence of postoperative complications and restricture.

Strictureplasty is a safe and efficacious procedure for small-bowel Crohn's disease in the long-term.