Lentil (Lens culinaris Medik.) is an excellent source of protein and carbohydrates and is also rich in essential trace elements for the human diet. Selenium (Se) is an essential micronutrient for human health and nutrition, providing protection against several diseases and regulating important biological systems. Dietary intake of 55 μg of Se per day is recommended for adults, with inadequate Se intake causing significant health problems. The objective of this study was to identify and map quantitative trait loci (QTL) of genes controlling Se accumulation in lentil seeds using a population of 96 recombinant inbred lines (RILs) developed from the cross “PI 320937” × “Eston” grown in three different environments for two years (2012 and 2013). Se concentration in seed varied between 119 and 883 μg/kg. A linkage map consisting of 1,784 markers (4 SSRs, and 1,780 SNPs) was developed. The map spanned a total length of 4,060.6 cM, consisting of 7 linkage groups (LGs) with an average distance of 2.3 cM between adjacent markers. Four QTL regions and 36 putative QTL markers, with LOD scores ranging from 3.00 to 4.97, distributed across two linkage groups (LG2 and LG5) were associated with seed Se concentration, explaining 6.3–16.9% of the phenotypic variation.

IntroductionLentil, Lens culinaris Medic., is an important cool season food legume in the old world. It is a self-pollinated, diploid (2n = 2x = 14) with a genome size of 4063 Mbp (Arumuganathan and Earl, 1991). The origin of cultivated lentil is the

Quantitative trait loci (QTLs) for flowering time (FT) in lentil were located using a recombinant inbreed line population derived from an intraspecific cross of Precoz × WA8649041. Experiments for FT were conducted in 2 locations (Haymana, Turkey and Pullman, WA, USA) for 5 years (from 1998 to 2002 in both Pullman and Haymana). A linkage map was constructed using 149 markers (RAPD, AFLP, ISSR, SSR, and 2 morphological markers) located on 11 linkage groups (LGs). Analysis of variance of FT was found to be significant for all locations and years. One major QTL for FT was identified on LG6 across all environments, indicating the stability of the QTL. The LOD scores for FT varied between 3.25 and 13.64 among the environments. The markers UBC318_2, SSR212_1, UBC220, M09a, and M09 on the QTL region were statistically significant in all environments. The SSR212_1 marker itself explained 57% of total genotypic variation according to the average of all environments, indicating the potential use of these markers in marker-assisted selection studies.

IntroductionLentil, which belongs to the family Leguminosae (Fabaceae), is an important food source for people around the world (Fikiru et al., 2007). Lentil represents the greatest source of protein after soybeans and hemp (Callaway, 2004). In addition to its nutritional importance, this crop plays a role in the fixation of nitrogen from the atmosphere and the formation of nitrogen in the soil, which replenishes nutrients and maintains soil productivity (Wong, 1980). Lentils are drought-tolerant (Karim Mojein et al., 2003) and are grown in many areas around the world. Geographically, this crop is widely cultivated in West Asia and the Indian subcontinent, North Africa, South Europe, South and North America, and Australia (Erskine, 1997). The major lentil-producing regions of the world are Asia and the West Asia/North Africa region (Erskine et al., 1998), and lentil is currently under cultivation in more than 35 countries (Yadav et al., 2007). Yadav et al. (2007) also reported that 99% of the world's lentil production is provided by 20 countries, with the most important lentilproducing countries being Australia, Canada,

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Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive lethal diseases among other cancer types. Gut microbiome and its metabolic regulation play a crucial role in PDAC. Metabolic regulation in the gut is a complex process that involves microbiome and microbiome-derived short-chain fatty acids (SCFAs). SCFAs regulate inflammation, as well as lipid and glucose metabolism, through different pathways. This review aims to summarize recent developments in PDAC in the context of gut and oral microbiota and their associations with short-chain fatty acid (SCFA). In addition to this, we discuss possible therapeutic applications using microbiota in PDAC.

Fine Mapping of Russian Wheat Aphid Resistance Gene in Bread Wheat (Triticum aestivum L.) * Bu makale birinci yazarın yüksek lisans tez çalışmasının sonuçlarından düzenlenmiştir.