Pulsed lasers at the near infrared (NIR) range have been widely used in dermatology. Ultrashort pulsed picosecond lasers are found with the specific ability of very effective activation of skin repair and remodeling along with significant photodamage. Femtosecond lasers, with a shorter pulse width, may be a promising alternative to current NIR lasers in clinic. In this study, we performed optical micromachining by a femtosecond laser at 1,030 nm to skin of live mice in two modes of scanning of focused laser and direct irradiation by unfocused laser. The acute and one-day delayed immune molecular responses of the skin to the micromachining are studied by immunofluorescence microscopy of the skin sections. Our data shows the focused laser can activate remodeling of skin without any significant immune responses. In contrast, the direct irradiation by the unfocused laser activate significant immune responses in the deep dermis with high regulation of interleukin. Those results suggest focused femtosecond laser is of good promising potential in activation of skin remodeling and repairing with little immune or physical damage.
Polarized structure color from thin dielectric gratings on an aluminum film is investigated. In the visible range, the −1st-order reflection of transverse electric (TE) light is higher than that of transverse magnetic (TM) light. Accordingly, the zeroth-order reflections for both polarizations behave distinctively such that TE-polarized light is chromatic while that for TM-polarized light is nearly white. Such chromatic and polarizing reflection predominantly comes from the Fabry-Perot interference between the interfaces of air/dielectric gratings and dielectric gratings/the metal region, which inhibits TM diffraction while facilitating TE diffraction. By further patterning the grating with a mask of an "apple," the central pattern is concealed when the polarization of the incident light is shifted from TE to TM. The characteristics of chromatic and polarizing reflection make this structure directly applicable in anticounterfeiting and decoration with the advantages of slim dimensions and easy fabrication.
Enhanced light-matter interaction of local field is of prime importance in optics, for it can improve the performance of nanophotonic devices. Such enhancement can be achieved by utilizing the optical...
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