The cause of the increased prevalence of diabetes mellitus is a change in lifestyle and socioeconomy. Family support is an important thing in the management of diabetes mellitus. One of the diabetes mellitus prevention program is a program of chronic disease managament (prolanis). The purpose of this study was to know the relationship between family support and activeness of prolanis participants with diabetes mellitus. This study used a correlative quantitative research design conducted in 2019 in Bandung. The samples in this study were 43 respondents. The sampling technique used in this study was total sampling. The data collected involved family support and activeness of participants by using a questionnaire instrument of family support and activeness of participants. Statistical test used Spearman Rank Correlation. The analysis result showed that there is a relationship between family support and activeness of participant level (P ≤ 0.05). It is suggested for government to educate about diabetes mellitus and how to care for it to the family of patients with diabetes melittus.