Latar belakang : Mengetahui karakteristik demografis pasien, hasil terapi yang diberikan dan menemukan faktor prediktor keberhasilan terapi pasien NOT di RSCM. Metode : Penelitian deskriptif menggunakan data sekunder dari telusur rekam medis pasien yang terdiagnosis NOT dari poliklinik Divisi Neuro-Oftalmologi (NO) Departemen Medik Mata FKUI/RSCM pada periode Januari 2014 hingga Desember 2015.
Hasil : Karakteristik demografik pasien NOT di RSCM ialah 82,4% laki-laki, dan rerata usia adalah 22,47 ± 10,68 tahun. Sebanyak 50% datang dalam rentang kurang dari 24 jam pasca trauma. Penurunan tajam penglihatan berat (58,8% NLP), 67,6% dengan RAPD positif, dan papil nervus optik yang bervariatif. Sebanyak 67,6% ditatalaksana dengan metilprednisolon intravena (1 g/hari selama 3 hari), 26,5% dengan metilprednisolon oral (0,8mg/kgBB/hari). Perbaikan tajam penglihatan dijumpai pada 32,4% pasien yang mendapatkan pengobatan selama satu bulan. Pasien close globe injury yang mendapat terapi < 24 jam secara statistik terjadi perbaikan tajam penglihatan (p = < 0.05).
Kesimpulan : Faktor prediktor seperti awitan trauma, awitan terapi inisial dan hasil pencitraan pada penelitian ini belum kuat untuk menjadi acuan dalam memprediksi keberhasilan terapi. Akan tetapi, pasien dengan closed globe injury yang diobati kurang dari 24 jam menunjukkan perbaikan tajam penglihatan yang signifikan. Dosis metilprednisolon IV 1 gram/hari selama 3 hari yang dilanjutkan dengan penirusan dosis per inggu maupun pemberian preparat oral dengan dosis 0.8 mg/KgBB/hari dapat digunakan. Pengobatan dilakukan setidaknya sampai dengan 1 bulan pasca pengobatan karena kurang baiknya kepatuhan pasien neuropati optik traumatic.
Objectives
This study aimed to investigate the spectrum of ocular characteristics and viral presence in the conjunctival swab of patients with COVID-19.
Methods
In this cross-sectional study, fifty-three patients were recruited from two COVID-19 referral hospitals in Jakarta (Cipto Mangunkusumo Hospital and Persahabatan Hospital) from July 2020 to March 2021. The inclusion criteria were patients who were suspected of or confirmed cases of COVID-19 with or without ocular symptoms. Demographic data, history of COVID-19 exposure, underlying medical condition, systemic symptoms, ocular symptoms, supporting laboratory results, reverse-transcriptase polymerase chain reaction (RT-PCR) of naso-oropharyngeal (NOP) swab and conjunctival swab were collected.
Results
Fifty-three patients who were suspected, probable or confirmed cases of Covid-19 were included. Forty-six out of 53 patients (86.79%) tested positive for either Covid-19 antibody rapid test or naso-oropharyngeal (NOP) swab. Forty-two patients tested positive for NOP swab. Fourteen out of 42 patients (33.33%) experienced symptoms of ocular infection including red eye, epiphora, itchy eyes, and eye discharge. None of these patients were tested positive for conjunctival swab. Two out of 42 patients (4.76%), who were tested positive for conjunctival swab, did not experience any ocular symptoms.
Conclusions
Establishing the relationship between Covid-19 infection, ocular symptoms, and presence of SARS-CoV-2 virus on the ocular surface proves to be challenging. In Covid-19 patients, ocular symptoms did not warrant a positive conjunctival swab result. On the contrary, a patient without ocular symptoms can also have detectable presence of SARS-CoV-2 virus on the ocular surface.
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