The Yatani mine has been generating acid mine drainage (AMD). AMD is formed through interactions between groundwater and sulfide minerals. The groundwater recharge area is located on the mountain slope of ~900 m.
These data suggest that mast cells play an important role in the onset of airway hyperreactivity but do not play a role in the production of IL-5 and eosinophilia. Furthermore, indicate that the inhibition of IL-5 is not always associated with a reduction in antigen-induced airway hyperreactivity in mice.
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