Spirulinal powder supplementation is being studied to see if it can help slow the progression of aging in the heart. As a control group, twenty male rabbits were randomly and equally divided into four groups, each receiving 150 mg/kg BW of d-galactose S/C daily as Group II; 500 mg/kg BW of Spirulinal orally as Group III; and 150 mg/kg BW daily S/C administration of d-galactose with 500 mg/kg BW orally as Group IV for four weeks. Using the specific stain Masson's Trichrome, stained sections of the aorta from the D-gal group (GII) and the combination group (CII) exhibit histological changes in the tissue (GIV). Tissue slices stained with Masson's Trichrome stain reveal the location of collagen and muscle fiber accumulation, which appears as a red keratin and muscle fiber accumulation area. Our findings show that Spirulinal powder, a feed supplement, has a protective effect against heart aging.
The aim of this study is to investigate the preventive role of food supplementation with Spirulina powder in the heart aging. Twenty male rabbits randomly and equally divided into four groups, normal as control group GI, animals received 150 mg/kg BW S/C daily of D-galactos as GII, animals were received 500mg/kg BW orally of Spirulina as GIII while GIV group was recived 150 mg/kg BW daily S/C administration of D-galactos with 500mg/kg BW orally of Spirulina for four weeks. The results of the study showed a significant decrease in Cardiac troponin I and Peroxynitrate with a significant increase in Nitric oxide and Glutathione in group received Spirulina compared with aging group GII. Conclusion, our result indicate the feed supplement of Spirulina powder caused preventive role against heart aging.
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