The spherical assemblies named “reverse micellar vesicles” from self-assembling psuedopeptidic bottlebrush polymers are reported. These assemblies exhibited the combined features of both micelles and vesicles viz. molecular arrangement of classical...

We, herein, report the fabrication of light-scattering switches from polymer microsphere-filled liquid crystals (PFLCs) using pseudopeptidic bottlebrush polymers. A simple method of precipitation of a polymer using the 4-cyano-4′-pentylbiphenyl (5CB) nonsolvent is employed for the preparation of PFLC devices. For this, a series of phenylalanine (Phe)-based bottlebrush polymers having different chain lengths are synthesized by ring-opening metathesis polymerization (ROMP) using the Grubbs second-generation ruthenium catalyst and used in a nematic liquid crystal (LC) matrix. The developed PFLC devices are well-characterized using various ultramicroscopic techniques such as field-emission scanning electron microscopy (FESEM), atomic force microscopy (AFM), and polarizing optical microscopy (POM). For the first time, the effect of the molecular weight of a polymer on electro-optic (E-O) properties of PFLC is investigated. PFLCs show significant differences in microsphere size, required operating voltage, transmittance, contrast ratio (CR ratio), memory effect, and switching speed upon subtle variation of the dopant polymer units. Overall, we demonstrated that the chain length of a polymer plays a crucial role in controlling the performance of PFLC devices. The presented methodology offers promising possibilities for the fabrication of PFLC-based switchable scattering devices with improved performance for optoelectronic applications.

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The development of synthetic scaffolds that nucleate well-folded secondary structures is highly challenging. Herein, we designed and synthesized a series of core-modified peptides (F1, F2, F3, and F4) that fold...

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We present a molecular topology-based strategy for creating pseudopeptosomes. These pseudopeptides showed cell penetrating property. X-ray crystal structure and spectroscopic data revealed a Trp zipper arrangement.

Long-lived coherences (LLCs) in a pair of coupled protons have long lifetimes and hence decreased line width and increased spectral resolution. Fourier transformation of the damped oscillatory decay of the LLC also provides coupling information on the spin system. In a three-spin system, unlike in the two-spin case, the peaks in an LLC spectrum are observed at combinations of the coupling constants. This attribute is used to determine the relative signs of the coupling constants in weakly and strongly coupled model systems. In addition, it is shown that a coupling constant in a three-spin system that is unobservable in the 1H NMR spectrum, as is the case in bispidinone, a molecule of significance in peptidomimetics, may be determined from the LLC spectrum.

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