Treatment with the Endurant stentgraft is technically feasible and safe, with satisfactory results in angulated and non-angulated anatomies alike. No sealing length was lost in extremely angulated cases, confirming the device's high conformability. Mid- and long-term data are awaited to verify durability, but early results are promising and challenge current opinion concerning neck angulation.
The treatment of patients with AAAs with the Endurant stent graft seems to be successful and durable during the first year after EVAR. Despite the wider inclusion criteria for the Endurant, and with 19% of our patients treated outside the IFU, the AAA-related mortality, number of type I or III endoleaks, and reintervention rates are comparable to the results of other stent grafts.
A new staging system for osteoradionecrosis of the mandible has been retrospectively applied to a group of 31 patients. In this system clinicoradiographic signs and symptoms are incorporated in a simplified manner. For imaging purposes the use of plain radiographs such as periapical films and panoramic radiographs is recommended, mainly because of their readily availability.
The presented staging system seems well reproducible, facilitating the comparison of study groups dealing with the various issues of osteoradionecrosis of the mandible. It is yet to be evaluated whether the presently proposed staging system is useful for management purposes.
Key words:Osteoradionecrosis, jaw bones, mandible, staging, classification.
We present a new autofluorescence-imaging method for bone analysis. This method, based on the autofluorescence of bone, provides color images in microscopic scale. The color images are created from three monochrome images acquired with optimal excitation-and emission-wavelengths combinations. The choice of these combinations were determined from the study of two-dimensional distributions of bone-features-bispectral autofluorescence in the visible-and ultraviolet-spectral range. We demonstrate that main-bone features visualized with MG-staining method can also be visualized in the autofluorescence-color image. Furthermore, the autofluorescence-color image presents features hardly distinguished in a histological-bone section.
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Objective:Mucins form a protective surface called mucosal pellicle on oral epithelium.Mucin -1 (MUC1) is secreted from the oral mucosal squamous epithelium itself on the apical surface of the epithelial cell. The objective of this study was to determine the effect of radiotherapy (RT) on MUC1 expression of the oral epithelium in patients with head and neck cancer (HNC) .Methods:Oral mucosal tissue biopsies were obtained from 55 patients; Study group 1 consisted of 33 clinically healthy subjects as controls. The oncology group consisted of two subgroups: Group 2 consisted of 7 oral cancer patients treated with surgery without RT, and Group 3 consisted of 15 HNC patients treated with RT. To visualized MUC1 staining, HMFG1 antibody was used. In addition, microstructures of the specimens were studied under electron microscopies.Results:The superficial layer of the oral epithelium had strong MUC1 staining in control samples compared to oncological groups (p=0.002) . Intermediate layer showed the most expression of MUC1 in irradiated mucosa (p=0.02) . In both oncological groups, the expression of MUC1 was detected on the basal layer (p=0.005) . Morphological analysis with electron microscopies showed destruction in the microstructure of apical cells of the irradiated oral epithelium. Irradiated oral mucosa with strong MUC1 expression showed loose intercellular bonds.Conclusion:Radiotherapy affects the expression of MUC1 in basal and intermediate layers of oral epithelium. Irradiation alters or hinders the intra and intercellular linkages which affects the normal apical transportation of MUC1 and hence, such alteration may play a role in promoting radiationinduced complications.
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