The James Webb Space Telescope (JWST) Early Release Observations (EROs) is a set of public outreach products created to mark the end of commissioning and the beginning of science operations for JWST. Colloquially known as the “Webb First Images and Spectra,” these products were intended to demonstrate to the worldwide public that JWST is ready for science, and is capable of producing spectacular results. The package was released on 2022 July 12 and included images and spectra of the galaxy cluster SMACS J0723.3-7327 and distant lensed galaxies, the interacting galaxy group Stephan’s Quintet, NGC 3324 in the Carina star-forming complex, the Southern Ring planetary nebula NGC 3132, and the transiting hot Jupiter WASP-96b. This paper describes the ERO technical design, observations, and scientific processing of data underlying the colorful outreach products.
This paper characterizes the actual science performance of the James Webb Space Telescope (JWST), as determined from the six month commissioning period. We summarize the performance of the spacecraft, telescope, science instruments, and ground system, with an emphasis on differences from pre-launch expectations. Commissioning has made clear that JWST is fully capable of achieving the discoveries for which it was built. Moreover, almost across the board, the science performance of JWST is better than expected; in most cases, JWST will go deeper faster than expected. The telescope and instrument suite have demonstrated the sensitivity, stability, image quality, and spectral range that are necessary to transform our understanding of the cosmos through observations spanning from near-earth asteroids to the most distant galaxies.
The James Webb Space Telescope (JWST) Early Release Observations (EROs) is a set of public outreach products created to mark the end of commissioning and the beginning of science operations for JWST. Colloquially known as the "Webb First Images and Spectra", these products were intended to demonstrate to the worldwide public that JWST is ready for science, and is capable of producing spectacular results. The package was released on July 12, 2022, and included images and spectra of the galaxy cluster SMACS J0723.3-7327 and distant lensed galaxies, the interacting galaxy group Stephan's Quintet, NGC 3324 in the Carina star-forming complex, the Southern Ring planetary nebula NGC 3132, and the transiting hot Jupiter WASP 96b. This paper describes the ERO technical design, observations, and scientific processing of data underlying the colorful outreach products.
Medicinal plants have been traditionally used to treat cancer in Ethiopia. However, very few studies have reported the in vitro anticancer activities of medicinal plants that are collected from different agro-ecological zones of Ethiopia. Hence, the main aim of this study was to screen the cytotoxic activities of 80% methanol extracts of 22 plants against human peripheral blood mononuclear cells (PBMCs), as well as human breast (MCF-7), lung (A427), bladder (RT-4), and cervical (SiSo) cancer cell lines. Active extracts were further screened against human large cell lung carcinoma (LCLC-103H), pancreatic cancer (DAN-G), ovarian cancer (A2780), and squamous cell carcinoma of the esophagus (KYSE-70) by using the crystal violet cell proliferation assay, while the vitality of the acute myeloid leukemia (HL-60) and histiocytic lymphoma (U-937) cell lines was monitored in the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) microtiter assay. Euphorbia schimperiana, Acokanthera schimperi, Kniphofia foliosa, and Kalanchoe petitiana exhibited potent antiproliferative activity against A427, RT-4, MCF-7, and SiSo cell lines, with IC50 values ranging from 1.85 ± 0.44 to 17.8 ± 2.31µg/mL. Furthermore, these four extracts also showed potent antiproliferative activities against LCLC-103H, DAN-G, A2780, KYSE-70, HL-60, and U-937 cell lines, with IC50 values ranging from 0.086 to 27.06 ± 10.8 µg/mL. Hence, further studies focusing on bio-assay-guided isolation and structural elucidation of active cytotoxic compounds from these plants are warranted.
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