Adipose stem cells (ASCs) have recently emerged as a more viable source for clinical applications, compared to bone-marrow mesenchymal stromal cells (BM-MSCs) because of their abundance and easy access. In this study we evaluated the regenerative potency of ASCs compared to BM-MSCs. Furthermore, we compared the dielectric and electro-kinetic properties of both types of cells using a novel Dielectrophoresis (DEP) microfluidic platform based on a printed circuit board (PCB) technology. Our data show that ASCs were more effective than BM-MSCs in promoting neovascularization in an animal model of hind-limb ischemia. When compared to BM-MSCs, ASCs displayed higher resistance to hypoxia-induced apoptosis, and to oxidative stress-induced senescence, and showed more potent proangiogenic activity. mRNA expression analysis showed that ASCs had a higher expression of Oct4 and VEGF than BM-MSCs. Furthermore, ASCs showed a remarkably higher telomerase activity. Analysis of the electro-kinetic properties showed that ASCs displayed different traveling wave velocity and rotational speed compared to BM-MSCs. Interestingly, ASCs seem to develop an adaptive response when exposed to repeated electric field stimulation. These data provide new insights into the physiology of ASCs, and evidence to their potential superior potency compared to marrow MSCs as a source of stem cells.
The technology scaling impact on FinFET-based Field-Programmable Gate Array (FPGA) components (Flip-Flops and Multiplexers) and cluster metrics is evaluated for technology nodes starting from 20[Formula: see text]nm down to 7[Formula: see text]nm. Power consumption, delay and energy (Power Delay Product, or PDP) trends are reported with FinFET technology scaling. Cluster metrics are then evaluated based on three benchmarking circuits: 2-bit adder, 4-bit NAND and cascaded flip-flops chain. The study shows that power, delay and PDP of the FPGA cluster are improved as we scale down the technology. An example for improvement is that for 7[Formula: see text]nm 2-bit adder, circuit speed is 15% higher than its value at 20[Formula: see text]nm and PDP at 7[Formula: see text]nm is reduced by 43% compared to its value at 20[Formula: see text]nm. The impacts of temperature and threshold voltage variations on FPGA cluster performance are also reported after evaluating a 2-bit adder circuit as a benchmark which is then used to calculate the design constraints to meet 99.9% yield percentage.
Thin film Si solar cell and surface plasmon polaritons (SPPs) effects on solar cell efficiency, series resistance and shunt resistance are studied and analyzed in this work. The different surface plasmon polaritons (SPPs) shapes and their effects on the optical, electrical properties and therefore on the efficiency of thin film solar cell are studied in this work. This study is introduced using 3D numerical simulation results. The semiconductor and electromagnetic models are incorporated for studying the electrical and optical behaviors of the thin film solar cells, respectively. A 14.76% efficiency is obtained for triangle' SPPs of about 1.07% of efficiency improvement compared to solar cell of SPPs free. The solar cell electrical parameters also are extracted in this work based on a single diode equivalent model. The series resistance is enhanced for solar cells of equilateral triangle SPP by 3% compared to the non-applied SPPs.
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