The increase of resistant bacteria puts a huge pressure on the antimicrobials in current use. Antimicrobial resistance (AMR) results from antibiotic misuse and abuse over many years and is a global financial burden. New polices must be developed for the use of antimicrobials and to continue research efforts to mitigate AMR. It is essential to target the most harmful bacteria and concentrate on their mechanisms of resistance to develop successful antimicrobials. Essential oils (EOs) are occur naturally in plants and have long been used as antimicrobials, but most have not been researched. This review explores EOs as alternative antimicrobials, investigating their ability to decrease or inhibit biofilm formation, and assess their ability to contribute to AMR control. Low concentrations of EOs can inhibit Gram-positive and Gram-negative pathogenic bacteria. Some EOs have demonstrated strong anti-biofilm activities. If EOs are successful against biofilm formation, particularly in bacteria developing AMR, they could be incorporated into new antimicrobials. Therefore, there is a need to investigate these EOs’ potential, particularly for surface disinfection, and against bacteria from food, clinical and non-clinical environments.

health of the intestine is one of the main reasons that affects the bird's performance, and thus the economic yield in the poultry sector. various studies have examined how to improve the intestinal health using dietary supplements, including organic acids such as sodium butyrate (sb). the efficacy of the dietary supplementation in poultry is often assessed using an important parameter such as intestinal integrity, which is often assessed as a measure of high villus height and the ratio of villus height to crypt depth, or count of goblet cell numbers. in broilers, the villus length and width were increased by the addition of dietary sb. since, at day 21 and 42, the villus length was increased by 55 and 27%, and 39 and 18% for birds fed 0.5 and 1 g/kg, respectively, compared with the control diet. furthermore, sb plays an important role in development of poultry intestinal epithelium. it can be employed by the intestinal epithelial cells as an energy source to stimulate their differentiation and proliferation, and to improve intestinal barrier function. sb is effective against acid intolerant species such as Salmonella, Clostridium perfringens and E. coli. in addition, use of butyric acid at 0.6% reduced the ph of gastrointestinal segments. for this, sb could be a potential alternative in maintaining the health of gastrointestinal tract and improving the productive performance of poultry. this review refers to the expanding horizons in the research on sb supplementation in poultry health and nutrition.

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Nanotechnology is one of the major advanced technologies applied in different fields, including agriculture, livestock, medicine, and food sectors. Nanomaterials can help maintain the sustainability of the livestock sector through improving quantitative and qualitative production of safe, healthy, and functional animal products. Given the diverse nanotechnology applications in the animal nutrition field, the use of nanomaterials opens the horizon of opportunities for enhancing feed utilization and efficiency in animal production. Nanotechnology facilitates the development of nano vehicles for nutrients (including trace minerals), allowing efficient delivery to improve digestion and absorption for better nutrient metabolism and physiology. Nanominerals are interesting alternatives for inorganic and organic minerals for animals that can substantially enhance the bioavailability and reduce pollution. Nanominerals promote antioxidant activity, and improve growth performance, reproductive performance, immune response, intestinal health, and the nutritional value of animal products. Nanominerals are also helpful for improving assisted reproductive technologies (ART) outcomes by enriching media for cryopreservation of spermatozoa, oocytes, and embryos with antioxidant nanominerals. Despite the promising positive effects of nanominerals on animal performance and health, there are various challenges related to nanominerals, including their metabolism and fate in the animal’s body. Thus, the economic, legal, and ethical implications of nanomaterials must also be considered by the authority. This review highlights the benefits of including nanominerals (particularly nano-selenium and nano-zinc) in animal diets and/or cryopreservation media, focusing on modes of action, physiological effects, and the potential toxicity of their impact on human health.