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Diurnal patterns of plasma triglycerides, free fatty acids, blood sugar and insulin were studied in 6 normal subjects and in 6 patients with the type IV hyperlipoproteinemia in order to assess the effect of a formula diet of balanced composition(19% protein, 37% fat, 44% carbohydrate) and of frequency of meal intake (3 versus 6 meals). In addition, the endogenous component of alimentary lipemia was estimated for the 24-hour period. The results demonstrate, that all-day levels of nutrients and insulin are similar with both meal patterns and that, regardless of feeding frequency, a considerable portion of ‘alimentary lipemia’ is contributed by pre-beta lipoprotein triglycerides.

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