This paper deals with the natural occurrence of aflatoxins in some common drug plants collected from storehouses in Bihar, India. Of 15 samples analyzed, 14 were aflatoxin positive. The highest level of aflatoxin contamination was detected in the seeds of Piper nigrum (1.20 ,ug/g), followed by the level detected in the seeds of Mucuna prurita (1.16 ,ug/g), and the lowest level was detected in the bark of Acacia catechu (0.09 ,ug/g). Of 158 isolates of Aspergillusflavus obtained from as many samples of drug plants, 49 were found to be toxigenic.
Samples of Cyperus rorundus. Gmelina arborea, Hygrophila spinosa. Mesua ferrea and Solanum nigrum were collected from different storage centers of Bihar (India). The common mycoflora isolated were species of Alrernaria. Aspergillus, Curvularia, Fusarium. Penicillium and Rhizopus. All the samples were analysed for natural aflatoxin contamination. Out of 37 samples screened 30 were found to be aflatoxin positive. Of 50 strains of Aspergillusflavus isolated from various samples, 21 were toxigenicand their potentiality to produce aflatoxin Blwas in the range of0.09 to 0.65pg/ml of culture filtrate.Pharmaceutical Biology Downloaded from informahealthcare.com by Nyu Medical Center on 12/07/14For personal use only.
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