* OBJECTIVE: To assess the effect of age and pupillary dilation on aqueous flare.
* METHODS: In this study, 100 eyes of 100 patients ranging in ages from 23 to 84 years were examined. Anterior chamber flare was measured before and after pupillary dilation using the Kowa laser flare meter (FM-500). Predilation and postdilation flare counts were compared by paired t-test. Stepwise regression analysis was then used to determine the effect of demographic variables on pre- and postdilation flare as well as the difference between preand postdilation flare counts.
* RESULTS: The predilation and postdilation flare counts correlated with age (/*<0.0001 for both preand postdilation flare counts). Correlation coefficient between age and flare measurements was R2=0.58 predilation and 0.63 postdilation. Flare intensity signifìcantly decreased after pupillary dilation (P<0.001).
* CONCLUSIONS: Anterior chamber flare increases with age. It might be related to blood-aqueous barrier instability. Pupillary dilation significandy decreases flare counts suggesting that aqueous protein concentration is dependent on aqueous flow rates.
[Ophthalmic Surg Lasers 2002;33:379-382]
* BACKGROUND AND OBJECTIVES: To determine the interobserver and intraobserver reproducibility of the laser flare meter and laser cell counter in assessing anterior chamber inflammation following cataract surgery.
* PATIENTS AND METHODS: Thirty-nine eyes with varied degrees of inflammation and 9 normal eyes were included in the study. Anterior chamber flare and cells were evaluated with the slit lamp and graded on a scale of 0 to 4+. The flare and cells were then measured three times each using the flare meter and cell counter by two different, experienced observers. The intraobserver reproducibilities were computed to evaluate repeatability of the instruments operated by the same observer. The first measurement taken by each observer was used to assess reproducibility between the two observers.
* RESULTS: The intraobserver reproducibility for overall flare was 0.995 for both observers. The intraobserver reproducibility for overall cells was 0.996 for observer 1 and 0.991 for observer 2. The overall interobserver reproducibility was 0.994 for flare and 0.988 for cells. The correlation between measurements and slit-lamp ratings was 0.78 for flare and 0.56 for cells.
* CONCLUSIONS: The intraobserver and interobserver reproducibilities were excellent, with good correlation to slit-lamp measurements. Reproducible results can be obtained using the laser flare meter and the laser cell counter. It is not known whether these results are applicable to other inflammatory processes with higher grades of flare and cells and with different protein and cell types.
[Ophthalmic Surg Lasers 1998;29:380-384.]
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