Previous studies have reported a relationship between being a victim of bullying, but no studies have been carried out with Mexican students; notwithstanding the high scores of bullying in Mexico in international rankings. The objective of this study was to analyze the association between being a victim of bullying and lower HRQoL among schoolchildren and adolescents in Mexico. This cross-sectional and correlational study involved 2225 students from 22 elementary, middle and high schools. HRQoL was assessed with the KIDSCREEN-10 questionnaire and bullying with the social adaptation dimension of KIDSCREEN-52. Bivariate associations were evaluated, and a multivariate logistic regression was utilized. The prevalence of victims of bullying was 17.3%. Being a victim of bullying was double the risk of having a lower HRQoL than not being a victim after adjusting for health perception, gender and age, OR 2.3 (1.7-3.1). As the Wilson and Cleary Model of Quality of Life explains, individual characteristics, such as, being a victim of bullying are associated with quality of life. Similar findings in the existing literature imply that bullying is a global phenomenon that impacts the victimized child or adolescent's life in different ways.
Hypertension and dyslipidemia exhibit an important clinical relationship because an increase in blood lipids yields an increase in blood pressure (BP). We analyzed the associations of seven polymorphisms of genes involved in lipid metabolism (APOA5 rs3135506, APOB rs1042031, FABP2 rs1799883, LDLR rs5925, LIPC rs1800588, LPL rs328, and MTTP rs1800591) with blood pressure and lipid values in Mexican hypertensive (HT) patients. A total of 160 HT patients and 160 normotensive individuals were included. Genotyping was performed through PCR-RFLP, PCR-AIRS, and sequencing. The results showed significant associations in the HT group and HT subgroups classified as normolipemic and hyperlipemic. The alleles FABP2 p.55T, LIPC −514T, and MTTP −493T were associated with elevated systolic BP. Five alleles were associated with lipids. LPL p.474X and FABP2 p.55T were associated with decreased total cholesterol and LDL-C, respectively; APOA5 p.19W with increased HDL-C; APOA5 p.19W and FABP2 p.55T with increased triglycerides; and APOB p.4181K and LDLR c.1959T with decreased triglycerides. The APOB p.E4181K polymorphism increases the risk for HT (OR = 1.85, 95% CI: 1.17–2.93; P = 0.001) under the dominant model. These findings indicate that polymorphisms of lipid metabolism genes modify systolic BP and lipid levels and may be important in the development of essential hypertension and dyslipidemia in Mexican HT patients.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.