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The factors governing the duration of ejection were studied by statistical techniques at rest and during exercise in man. Data consist of 207 points in 20 subjects. Linear stepwise regression analysis results in the following formula for the prediction of the duration of ejection from the heart rate, stroke index, and the aortic diastolic pressure: duration of ejection = .36646 - .00108 (rate) - .00036 (diastolic pressure) + .00076 (stroke index). The correlation coefficient is 0.90 on comparison with the measured duration of ejection. The error of estimate is .0155 sec. The validity of the three variables was confirmed by factor analysis. Heart rate was found to be the major determinant of the duration of ejection. Stroke index and pressure have a relatively minor but statistically significant effect. ventricular ejection time prediction and calculation; factor analysis of ventricular ejection; cardiac output during exercise; heart rate, stroke index, and ventricular ejection; aortic diastolic pressure and ventricular ejection Submitted on July 18, 1963

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