Background: Diabetes mellitus refers to a grouping of metabolic diseases involving prolonged hyperglycemia caused by the inadequate secretion of insulin, poor insulin action, or a combination of the two. Poor glycaemic control is a major public health problem among patients with type 2 diabetes mellitus.Objective: To expose the incidence and predictors of poor glycemic control among adults with type 2 diabetes mellitus in ambulatory clinic of Mettu Karl Referral Hospital.Methods: An institutional based prospective cross-sectional survey was carried out from April 23/2020 to June 24/2021. Data was collected through employing structured questioner, and then the collected data was cleared, coded and analyzed by statistical packages for social sciences 25.0 version statistical software. Descriptive statistics such as the frequency and percentage were used. Those variables with p-value less than 0.25 in bi-variable analysis were entered into multivariable analysis. A p-value of less than 0.05 was considered significant.Results: A total of 122 patients with type 2 diabetes mellitus were included in this study. The overall incidence of poor glycemic control among type 2 diabetic patients was 60.7%.Poor glycemic control was significantly associated with older age (AOR= 2.

Background: The COVID-19 pandemic is expected to continue to impose enormous burdens of morbidity and mortality while severely disrupting societies and economies worldwide. Vaccines are a key strategy to stop the escalation of the COVID-19 pandemic. Vaccines are the effective way to control and prevent a several diseases, save lives, and reducing current health emergency, as well as increasing the immunity of the population. Objective: To find out eagerness to acceptance of COVID-19 vaccine among health care workers in oromia regional state, Ethiopia: An online-based cross-sectional study. Methods: An online based cross sectional study design were carried out from April 18, 2021 to June 19, 2021. Data was collected through employing online questioner, and then the collected data were coded and analyzed by statistical packages for social sciences 25.0 version statistical software. The statistical significance was set at a P-value ≤0.05. Findings: The current study revealed that 178 (42.2%) of health care workers intended to receive the COVID-19 vaccines. The results of our study showed that the majority of participants don’t believe that COVID-19 vaccine is effective and safe (n=279.66.1%), and couldn’t save lives (n=228, 54.1%). Factors such as age group >55 (AOR: 2.75; 95% CI: 1.092-5.472; P=0.008), Female(AOR: 1.86; 95% CI: 1.243-2.796; P=0.003), nurses (AOR: 2.17; 95% CI: 0.621-5.087; P=0.0094) and midwives (AOR: 2.521; 95% CI: 2.497-8.24; P=0.0002), married (AOR: 1.74; 95% CI: 0.218-4.530; P=0.006), health care workers who had contact with COVID-19 patient were twice as likely to accept the vaccine (AOR: 1.93; 95% CI: 1.360- 3.784; P=0.0001) and health care workers who indicated that they had more serious medical condition (AOR: 2.61; 95% CI: 0.981-3.618; P=0.007) proved to be significant predictors of the acceptability of the COVID-19 vaccine. Factors such as taking vitamin C (AOR: 1.624; 95% CI: 0.945-2.596; P=0.0003), poor safety of vaccines (AOR: 7.041; 95% CI: 3.692-13.375; P=0.000), those believe effective medicine avail for treating COVID-19 (AOR: 2.16; 95% CI: 1.596-3.485; P=0.0076), no adequate trials about COVID-19 (AOR: 7.041; 95% CI: 3.692-13.375; P=0.000), and unwanted side effects of the vaccines (AOR: 3.422; 95% CI: 1.448-8.096; P=0.005) were identified as indicators why health care workers would decline uptake of COVID-19 vaccines. Conclusion and Recommendation: Our survey revealed that the eagerness to acceptance of covid-19 vaccine among health care workers in oromia regional state was somewhat meagre. Nurses and Midwives were more likely to accept the COVID-19 vaccines than others health care workers. Oromia health bureau should have to give training about COVID-19 vaccine to all health care workers.

Introduction: Physiological alterations during pregnancy as well as the bio- conversion of compounds can significantly influence the teratogenic effects of drugs and chemicals by affecting absorption, body distribution, the active form(s), and excretion of the compound. Certain medications may cause harm to the foetus due to their potential teratogenic effects and the physiological adjustments occurring in the mother during pregnancy. Prescription of drug used by pregnant women should be viewed as one of a public health issue. This study aware health care workers on harmful drugs prescription to pregnant women and helps in understanding the type of medication used during pregnancy and safety of drugs used during pregnancy, thereupon this study was ascertain drug usage pattern and potential teratogenicity risk among pregnant women attending maternal and child health clinic of Mettu Karl Referral Hospital. Methods: A hospital-based cross-sectional study design was carried out from April 13/2021 to June 15/2021. Data was collected through employing semi-structured questioner, and then the collected data was cleared, coded and analyzed by statistical packages for social sciences 25.0 version statistical software. Descriptive statistics were used to describe the data. P value <0.05 was considered as a cut point for statistical significance in the final model. Results: A total of 156 participants were interviewed of whom, 81(51.9%) pregnant women were age between 20-35 years old and a majority 113(72.4%) of them were married. Among medical condition majority 40(25.6%) of the participants had peptic ulcer disease and 26(16.7%) urinary tract infections followed by 20(12.8%) acute illness and 12(7.7%) hyperemesis. Among the total drug prescribed for pregnant women 30(19.2%) FDA category C was the common followed by 29 (186%) FDA category B and 26(16.7%) FDA category D. Only 10(6.4%) of prescribed drug were FDA category X. Pregnant women whose age >35 years (AOR=4.05, 95%CI:1.274-1.903; p=0.001), urban residents (AOR=2.72, 95%CI:2.524-3.927; p=0.035), and pregnant women during second trimester (AOR=1.79, 95%CI:3.926-9.406; p=0.013) were significantly associated with MCH follow up. Conclusion and recommendation: From the drug prescribed, majority of pregnant women were taken antibiotics followed by 18(11.5%) NSAID, iron sulfate, and proton pump inhibitors. Among the dosage form, above half of the participants were taken the tablet dosage form followed by capsule and gels dosage form. Health care workers should have to brought good care for pregnant women, since they perhaps vulnerable to drug teratogenesity

Background: Non-communicable diseases are defined as diseases or conditions, which affect individuals over an extended period of time (years, decades or even an entire lifetime) and for which there are no known causative agents that are transmitted from one affected individual to another. Noncommunicable diseases are a major global problem. Objective: To find out magnitude and determinants of non-communicable disease and its contributing factors in medical ward of Mettu Karl Referral Hospital. Methods: A prospective observational study design was conducted from April 23/2021 to June 24/2021. Data was collected through employing structured questioner, and then the collected data was coded and analyzed by statistical packages for social sciences 25.0-version statistical software. A test of association was done using binary and multiple logistic regressions. P value <0.05 was considered significant. Findings: The overall prevalence of non-communicable disease in medical ward was 288 (68.2%).Hypertension was the commonest type of noncommunicable disease 41.71% followed by diabetes mellitus 41.5%. Regarding body mass index majority 153 (36.3%) of patients were normal (18.5-24.9 kg/m²) and least 57 (13.5%) of the patients were underweight (<18.5kg/m²). Age, every khat chewers, every alcohol drinkers, BMI ≥thirty kg/m², biochemical risk factors (obesity, high blood pressure, high fasting blood sugar, low density lipoprotein, and comorbidity were significantly predictors of non-communicable diseases). Conclusion and Recommendation: Majority of patients had physical activity ten minutes per day, had sedentary lifestyle ten to thirty hours per week, were walking ten to thirty hours/per week, and above half of patients were use salt always/usually. Health care workers should have teach the patients how to prevent non-communicable diseases.

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