No abstract

Bisphosphonates are drugs that suppress bone turnover and are commonly prescribed to prevent skeletal related events in malignancy and for benign bone diseases such as osteoporosis. Bisphosphonate associated jaw osteonecrosis (ONJ) is a potentially debilitating, yet poorly understood condition. A literature review was undertaken to review the dental clinical implications of bisphosphonates. The present paper briefly describes the postulated pathophysiology of ONJ and conditions with similar clinical presentations. The implications of bisphosphonates for implantology, periodontology, orthodontics and endodontics are reviewed. Whilst bisphosphonates have potential positive applications in some clinical settings, periodontology particularly, further clinical research is limited by the risk of ONJ. Prevention and management are reviewed, including guidelines for reducing cumulative intravenous bisphosphonate dose, cessation of bisphosphonates prior to invasive dental treatment or after ONJ development, and the use of serum beta-CTX-1 in assessing risk. In the context of substantial uncertainty, the implications of bisphosphonate use in the dental clinical setting are still being determined.

A compromised oral health condition amongst patients with special health care needs (SHCN) has been associated with the reluctance and shortage of skills of dental professionals in managing such patients. Lack of training and experience at the undergraduate level are reported barriers to the provision of care for this patient cohort. Undergraduate education therefore, plays an important role in producing professionals with the knowledge, skills and positive attitude in treating patients with SHCN. This study aims to determine the level of knowledge, comfort and attitudes of Malaysian undergraduate dental students towards caring for patients with SHCN, as well as their perception on education in this field. A self-administered questionnaire was administered in the classroom style to final year undergraduate dental students in Malaysian public dental schools. Most students were aware of Special Needs Dentistry (SND) as a specialty after being informed by academic staff. The majority of the students demonstrated poor knowledge in defining SND and felt uncomfortable providing care for such patients. They perceived their undergraduate training in SND as inadequate with most students agreeing that they should receive didactic and clinical training at undergraduate level. A high percentage of students also expressed interest in pursuing postgraduate education in this area of dentistry despite the lack of educational exposure during undergraduate years. The study supports a need for educational reform to formulate a curriculum that is more patient-centred, with earlier clinical exposure in various clinical settings for students to treat patients with special health care needs, applying the concept of holistic care in a variable clinical condition.

General anesthesia is commonly used to facilitate dental treatment in patients with anxiety or challenging behavior, many of whom are children or patients with special needs. When performing procedures under general anesthesia, dental surgeons must perform a thorough pre-operative assessment, as well as ensure that the patients are aware of the potential risks and that informed consent has been obtained. Such precautions ensure optimal patient management and reduce the frequency of morbidities associated with this form of sedation. Most guidelines address the management of pediatric patients under general anesthesia. However, little has been published regarding this method in patients with special needs. This article constitutes a review of the current literature regarding management of patients with special needs under general anesthesia.

The aims of this study were to assess the effect of clenching with or without the presence of an interocclusal appliance (IOA) on bite force (BF) and masseter electromyography (EMG) in patients with temporomandibular pain dysfunction disorders (TMPD) and to compare these results with an asymptomatic age- and gender-matched control group. Ten patients with TMPD (mean age 26.9 years) were compared with eight healthy controls (mean age 25.3 years). Bilateral masseter EMG activity was recorded at rest, while clenching on the BF meter, while clenching on an IOA and while clenching on an IOA together with the BF meter. Significant left to right EMG activity asymmetry was found in the patient group at rest and during multiple clenching tasks in the control group. The patient group had significantly greater EMG activity at rest than controls. For all other tasks, the control group EMG activity was greater than the patient group. Use of an IOA significantly decreased EMG activity in both patient and control groups. BF was significantly greater in the control group on the right side for the different clenching tasks. Insertion of the IOA significantly increased BF in the control group. The results of this study indicate differences in EMG activity and BF during different clenching tasks and between patients with TMPD and asymptomatic subjects.

PURPOSE Medication-related osteonecrosis of the jaw (MRONJ) is an infrequent but morbid and potentially serious condition associated with antiresorptive and antiangiogenic therapies. Although MRONJ can be prevented by optimizing oral health, management of established cases is supportive and remains challenging. Teriparatide, an osteoanabolic agent that improves bone healing in preclinical studies and in chronic periodontitis, represents a potential treatment option. PATIENTS AND METHODS In a double-blind, randomized, controlled trial, 34 participants with established MRONJ, with a total of 47 distinct MRONJ lesions, were allocated to either 8 weeks of subcutaneous teriparatide (20 µg/day) or placebo injections, in addition to calcium and vitamin D supplementation and standard clinical care. Participants were observed for 12 months, with primary outcomes that included the clinical and radiologic resolution of MRONJ lesions. Secondary outcomes included osteoblastic responses as measured biochemically and radiologically and changes in quality of life. RESULTS Teriparatide was associated with a greater rate of resolution of MRONJ lesions (odds ratio [OR], 0.15 v 0.40; P = .013), and 45.4% of lesions resolved by 52 weeks compared with 33.3% in the placebo group. Teriparatide was also associated with reduced bony defects at week 52 (OR, 8.1; P = .017). The incidence of adverse events was balanced between groups, including nausea, anorexia, and musculoskeletal pain, most of mild severity. CONCLUSION Teriparatide improves the rate of resolution of MRONJ lesions and represents an efficacious and safe treatment for it.

Special Needs Dentistry has recently been recognised as a dental specialty in Australia. In states other than Victoria, New South Wales and South Australia, this patient cohort would predominately be managed by the general dentist, making a study into aspects of their perception with this patient group pertinent in other States of Australia. This is further reinforced by the fact that there are no registered Special Needs specialists in Western Australia. This study aims to investigate the perception of Special Needs Dentistry amongst general dental practitioners in Western Australia. Materials and methods: A postal questionnaire was distributed to 1000 dentists practicing in Western Australia. The questionnaire recorded sociodemographic characteristics, perceptions of Special Needs Dentistry (awareness and definition), perception of Special Needs Patients (clinical exposure according to the categories of aged care, physically disabled, intellectually disabled, medically compromised, infectious diseases, and psychiatric problems), criteria for referral of Special Needs Dentistry patients, and perception of Special Needs Dentistry education. Quantitative data was analysed using Chi-squared statistical analysis (p ≤ 0.01). Results: Approximately a third of dentists received undergraduate training in Special Needs Dentistry. The majority demonstrated adequate knowledge in defining Special Needs Dentistry and reported providing treatment to such patients. Inadequate experience and difficulty in managing behavioural problems were quoted as the main reasons for not treating patients with SN, although a high percentage of dentists felt positive in providing treatment to most groups except those with psychiatric issues. While most dentists expressed interest in undergoing continual professional development courses in Special Needs Dentistry, most were not keen on pursuing postgraduate education in this field. Conclusion: Dentists in WA were variable in their approach to those with special needs. University curricula and continual professional development in Special Needs Dentistry may improve dentists' knowledge, attitudes and skills in managing these patients. However, in order to further direct the growth of Special Needs Dentistry, more research is needed into factors that may influence dentists' willingness to treat this patient cohort.

Meeting the oral health care needs of the growing population of people with special health care needs (SHCN) starts with dental students' acquisition of sound knowledge and development of clinical competence at the predoctoral level. The aim of this study was to review the level of undergraduate education in Special Needs Dentistry (SND) in Malaysian and Australian dental schools. The deans of all six Malaysian public dental schools and eight of nine Australian dental schools participated in a postal survey on current undergraduate didactic and clinical training in SND at their institutions. The results showed the number of dental schools in Malaysia with teaching in SND as a speciic discipline was relatively low compared to that of Australia. However, a high percentage of Malaysian and Australian dental schools reported incorporating teaching of SND into pediatric dentistry (83.3 percent vs. 75 percent), oral medicine/oral pathology (66.7 percent vs. 75 percent), and oral surgery (66.7 percent vs. 25 percent). Most respondents said their school delivered SND clinical training in dental school clinics, hospital-based settings, and residential aged care facilities. Respondents in both countries viewed lack of faculty expertise as the greatest barrier to providing SND education. The study provides valuable information that can direct SND curriculum development in the two countries.