The altered pattern of sleep in individuals with CP directly affects their physical and emotional well-being.
The aim of this study was to investigate the correlation between sleep disorders and the behavior of subjects with autism spectrum disorder (ASD) and control subjects using specific questionnaires. A small percentage (1.8%) of the control subjects had symptoms indicative of sleep-breathing disorders (SBD) and nocturnal sweating. Fifty-nine percent of the subjects with ASD had symptoms indicative of at least one sleep disorder, with SBD the most commonly reported (38%). In the control group, the symptoms of SBD were correlated with social, thought, attentional, aggression, externalizing and behavioral problems. In the ASD group, disorders of arousal (DA) were correlated with thinking problems, and disorders of excessive somnolence were correlated with thinking and behavioral problems. These results suggest that children and adolescents with ASD have a high frequency of sleep disorders, which in turn correlate with some of the behavioral traits that they already exhibit. Furthermore, sleep disturbances, when present in the typically developing children, also correlated with behavioral problems.
Among the most co-occurring conditions in autism spectrum disorders (ASD), there are sleep disorders which may exacerbate associated behavioral disorders and lead to intensification of existing autistic symptoms. Several studies investigating the use of melatonin in the treatment of sleep disorders in ASD have shown comparative efficiency in sleep with little or no side effects. Here we report a case of ASD with non-24-hour rhythm and the effect of melatonin in circadian parameters by actigraphy. Visual analysis of the first 10 days recorded and the periodogram suggest that this patient showed a non-24-hour rhythm. This ASD subject showed before melatonin administration an activity/rest rhythm lower than 24 hours. The results show that melatonin increased approximately 4.7 times the regularity of circadian activity rhythm and resting staying on average between 00:00 and 06:00 and showed positive effects in improving the quality of sleep and behavior. So, the actigraphy showed an ASD subject with a non-24-hour activity/rest rhythm which changed this rhythm to a 24-hour rhythm after melatonin administration. This result reinforces the prospect of therapy with melatonin for synchronization (increased regularity) of endogenous rhythms and improve sleep quality and hence behavior and indicates the actigraphy as a choice tool to characterize several parameters of the activity/rest rhythm of ASD individuals.
Introduction: Attention deficit hyperactivity disorder (ADHD) leads to cognitive problems in childhood and adolescence, and due to its associated hyperkinesias, it may also result in behavioral problems, which can lead to negative impressions amongst one's peers. Objective: To assess the impact of hyperkinesia reduction on the attention and behavior profiles of three children with the combined type of ADHD following an intervention featuring psychoactive medication. Methods: This pilot study was conducted at the Laboratory of Learning Difficulties and Disabilities and Attention Disorders (DISAPRE-UNICAMP). Objective data (including mean values of amplitude and frequency of movement over 24 hours) were obtained using an actigraph (a clock-like device), a behavioral assessment scale (the Child Behavior Checklist [CBCL]), and the Strength and Weakness and ADHD Symptoms Normal Behavior (SWAN) rating scale (which was administered by clinicians and school staff members); these were cross-referenced to compare the children's performance before and after the use of psychoactive medication. The treatment was introduced after 15 days and maintained thereafter for 30 days, and the results were statistically analyzed by means of actigraphic variables (L5 and M10) and by student's t-test (P < 0.05). Results: There was a simultaneous reduction in the actigraphic index, the attention deficit scores of hyperactivity for both the CBCL and SWAN, and the somatic disorder symptom scores of the CBCL. These results were statistically significant when ex- 1977 Psychology amining the pre-and post-medication data for each individual in the sample. Conclusion: The reduction in hyperkinesias in the three patients with ADHD resulted in improvements in inattention, somatic symptoms, and emotional symptoms.
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