BACKGROUNDAlcoholic Liver Disease (ALD) includes a wide range of injury from reversible steatosis, steatohepatitis to irreversible cirrhosis. Alcoholic hepatitis is a very important entity, because severe alcoholic hepatitis is associated with a high short term mortality rate of 40-45%, which is unacceptable and has to be prevented. So far the severity of alcoholic hepatitis is identified by calculating 'Modified Discriminant Function' (mDF) score. This score includes only Prothrombin Time (PT) and bilirubin in calculating the severity of alcoholic hepatitis. MDF of greater than or equal to 32 is considered severe and treated with steroids and pentoxifylline. New scoring system 'Glasgow Alcoholic Hepatitis Score (GAHS) which includes age, white cell count, urea, PT and serum bilirubin level is used in identifying the patients in need of drug therapy.
BACKGROUNDCirrhosis of liver results in portal venous hypertension and ooesophageal varices when decompensated. The present study aims to study the non-invasive clinical, biochemical and ultrasonographic parameters to predict the risk of ooesophageal varices to correlate platelet count/splenic diameter ratio with grade of varices and to study the type of anaemia picture in cirrhotics.
BACKGROUNDIschemic strokes account for >80% of total stroke events. Biochemical modalities like serum uric acid, ESR, CRP, Serum Fibrinogen will be a low cost and useful way to predict functional outcome after ischemic stroke. The Barthel ADL index it is an ordinal scale helping us to measure performances in ADL-activities in daily living. The present study aims to study the Biochemical parameters Uric Acid, CRP, ESR and Fibrinogen in Ischemic Stroke patients and to assess functional outcome in these patients using Barthel Index at admission and at discharge.
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