Arterial pressure was measured in 94 adult patients with polycystic kidney disease (PKD) and the data obtained were compared with those of two groups of patients with other chronic renal diseases. Patients with PKD having a glomerular filtration rate within normal limits were more frequently hypertensive than those with other renal diseases. This relationship was reversed when patients with severe renal insufficiency were considered.
A group of patients with severe anemia on standard hemodialysis were transferred to polyacrylnitrile hemodiafiltration (HDF), which was arranged in order to obtain an ultrafiltration rate (UF) higher than 100 ml/min. During HDF, despite a significant reduction of the dialysis time, all patients had a significant decrease of predialytic BUN and serum creatinine, and a significant improvement of anemia. Furthermore, a close direct correlation was detected between the percent increase of hemoglobin and the length of time on HDF. Therefore, high-UF HDF represents a valid dialytic strategy to improve anemic states, permitting a significant reduction of the dialysis time and, thus, offering a better life quality for the patients.
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