A new procedure for fast quantitative extraction of cell parameters from diffraction patterns was deduced from model calculations and applied to cervical gynecological material. Based on radial scans of the diffraction pattern, the technique permits simultaneous determination of the nuclear and cytoplasmic diameters by Fourier analysis of the radial scanning signals after compensation for the intensity falloff by an amplification proportional to the third power of the radial position in the diffraction plane. Illustrative examples of measurements on exfoliated cells of different types are presented.
Measurements of tile absorption coefficient and the refractive index of crystalline lithium fluoride have been carried out in the infrared region between 300 and 900 microns wavelength. The spectrometer which has been used was of the periodic interference-modulator type. Some general properties of this instrument are described.
In this report, a preselection of alarms in a system for automated screening of cervical cancer based on depositing the cell sample linearly as a "cell trace" on a tape and analyzing it at different decision levels with increasing complexity, and preliminary results on analyzing cervical material with this system are discussed. The "cell trace" is analyzed with the slit-scan technique. Six parameters are computed: 1) cellular diameter; 2) nuclear diameter; 3) nuclear fluorescence (acriflavin-Feulgen) as nuclear DNA; 4) cellular fluorescence; 5) nuclear to cytoplasm ratio (N/C ratio); and 6) nuclear density. At present, only nuclear fluorescence is used to define a decision boundary between normal and potentially atypical cells. Under this criteria the slit-scan analysis leaves 5% of the events in a sample that must be rechecked at a second decision level in normal cell samples. A further reduction is expected when several slit-scan parameters are used at the first decision step. All events declared suspicious will be investigated in more detail by a two dimensional image analyzing system where the fluorescence image is generated by a laser scanning system. Results obtained in preliminary experiments are discussed in this paper.
Under contract with the German Federal Ministry for Research and Technology, Battelle-Frankfurt developed a fiber-optic flowmeter operating according to the principle of two-beam laser-Doppler anemometry. The function of this apparatus is to monitor slowly flowing inorganic and organic solvents during the reprocessing of nuclear fuels.
In der vorliegenden Arbeit wird fiber Absorptionsmessungen an CsBr und CaF 2 im Spektratbereich zwischerl 0,4 und 3,5 mm Wellent~nge berichtet, Die Messungen erfolgten an planparallelen Platten mittels eines Interferenzmodulator-Spektrometers mit thermischem Strahler und mittels eines optischen Mikrowellen-Spektrometers mit einer Vervielfacheranordnung als Strahlungsquelle. Als Resultat wird der Absorptionskoeffizient k angegeben. Es zeigt sich, dab sein Verlauf nicht durch klassische Dispersionsformeln dargestellt werden kann.
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