BackgroundCrimean Congo Hemorrhagic Fever (CCHF) is a life threatening acute viral infection that presents significant risk of nosocomial transmission to healthcare workers.AimEvaluation of CCHF infection prevention and control (IP&C) practices in healthcare facilities that routinely manage CCHF cases in Eurasia.MethodsA cross-sectional CCHF IP&C survey was designed and distributed to CCHF centers in 10 endemic Eurasian countries in 2016.ResultsTwenty-three responses were received from centers in Turkey, Pakistan, Russia, Georgia, Kosovo, Bulgaria, Oman, Iran, India and Kazakhstan. All units had dedicated isolation rooms for CCHF, with cohorting of confirmed cases in 15/23 centers and cohorting of suspect and confirmed cases in 9/23 centers. There was adequate personal protective equipment (PPE) in 22/23 facilities, with 21/23 facilities reporting routine use of PPE for CCHF patients. Adequate staffing levels to provide care reported in 14/23 locations. All centers reported having a high risk CCHFV nosocomial exposure in last five years, with 5 centers reporting more than 5 exposures. Education was provided annually in most centers (13/23), with additional training requested in PPE use (11/23), PPE donning/doffing (12/23), environmental disinfection (12/23) and waste management (14/23).ConclusionsStaff and patient safety must be improved and healthcare associated CCHF exposure and transmission eliminated. Improvements are recommended in isolation capacity in healthcare facilities, use of PPE and maintenance of adequate staffing levels. We recommend further audit of IP&C practice at individual units in endemic areas, as part of national quality assurance programs.

HighlightsCCHF in pregnancy is rare but has high rates of maternal (34%) and fetal mortality (59%).Maternal hemorrhage is associated with maternal and fetal/neonatal death.Nosocomial transmission of CCHF from 6/37 index pregnant cases resulted in 38 cases.Early recognition and risk-assessment allows appropriate IP & C precautions and supportive care provision.

We performed a systematic review and meta-analysis on the effectiveness of ribavirin use for the prevention of infection and death of healthcare workers exposed to patients with Crimean-Congo hemorrhagic fever virus (CCHFV) infection. Splashes with blood or bodily fluids (odds ratio [OR] 4.2), being a nurse or physician (OR 2.1), and treating patients who died from CCHFV infection (OR 3.8) were associated with healthcare workers acquiring CCHFV infection; 7% of the workers who received postexposure prophylaxis (PEP) with ribavirin and 89% of those who did not became infected. PEP with ribavirin reduced the odds of infection (OR 0.01, 95% CI 0–0.03), and ribavirin use <48 hours after symptom onset reduced the odds of death (OR 0.03, 95% CI 0–0.58). The odds of death increased 2.4-fold every day without ribavirin treatment. Ribavirin should be recommended as PEP and early treatment for workers at medium-to-high risk for CCHFV infection.

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diagnosed because of failure or relapsed with adhering first line regimens. The results of drug susceptibility in adults index cases can guide the treatment in children, however, most were lacking. The molecular technique currently available is not much more useful over culture.-Control: The best control measures for childhood TB are to treat adults and pregnant women promptly, and perform contact investigation. Treatment of latent tuberculosis is helpful and should be given to all children younger than five who exposed to TB. The usefulness of PPD skin test for diagnosing latent tuberculosis is limited in children in settings that provide routine neonatal BCG vaccination. Quantiferon test is expensive and not sensitive in young children. HIV makes TB worse and vice a versa. Appropriate anti-retroviral therapy is needed to control TB.http://dx.

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О ценка объема, временной динамики и структуры запросов в Google, Facebook, Twitter широко используется для понимания интересов населения во время эпидемии, а также для целей здравоохранения [1][2][3][4][5][6][7][8]. В частности, Google Trends позволяет анализировать и прогнозировать такие важные вопросы здравоохранения, как распространение СПИДа, самолечение с помощью лекарств и ментальное здоровье [9]. В предыдущей работе [10] нами было показано, что поисковая активность по запросам, которые могут быть связаны Инфодемиологическое исследование эпидемии коронавируса с использованием Google Trends в странах Центральной Азии -Казахстане, Киргизии, Узбекистане, Таджикистане К. Т. Момыналиев, д. б. н., доцент, вед. н. с. организационно-методического отдела 1 Л. Л. Хоперская, д. п. н., проф. кафедры международных отношений 2 Н. Ю. Пшеничная, д. м. н., проф., зам. директора по клинико-аналитической работе 1 Г. Н. Абуова, к. м.н, проф., зав. кафедрой инфекционных болезней и дерматовенерологии 3