Crimean-Congo hemorrhagic fever in pregnancy: A systematic review and case series from Russia, Kazakhstan and Turkey

Pshenichnaya, N.; Leblebicioğlu, Hakan; Bozkurt, İlkay; Sannikova, I. V.; Abuova, G.; Журавлев, А. С.; Barut, Sener; Shermetova, Mutabar Bekovna; Fletcher, Tom

doi:10.1016/j.ijid.2017.02.019

Cited by 37 publications

(28 citation statements)

References 28 publications

(33 reference statements)

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“…Here, we were only able to examine female reproductive tissues, so whether these findings extend to male reproductive tissues and any implications for sexual transmission remain to be determined. Several reports focused on CCHF in pregnant women and outcomes in neonates [34][35][36][37][38][39], but to date, there is only one report of potential sexual transmission [40]. Our data support future investigations into reproductive infection, pathology, and implications for CCHFV transmission, as well as using both female and male models of disease for these and other pathogenesis studies.…”

Section: Differential Cytokine Expression In Mice Infected With Eithesupporting

confidence: 74%

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

et al. 2019

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Section: Differential Cytokine Expression In Mice Infected With Eithesupporting

confidence: 74%

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

et al. 2019

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“…In another report, two pregnant patients in Turkey survived and gave birth to healthy babies by vaginal delivery [76] . A review of pregnant patients reported that maternal mortality was 34% (14/41) and fetal/neonatal mortality was 58.5% (24/41), and the presence of hemorrhage was associated with maternal and fetal mortality [77] .…”

Section: Prognostic Factors Fatality and Discharge Criteriamentioning

confidence: 99%

Crimean-Congo Hemorrhagic Fever

Kazancıoğlu¹,

Akıncı²,

Bodur³

2018

mjima

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“…The disease was first reported in 1944. However, CCHF transmission has been reported globally since 1998 [6]. Today, the infection is endemic, with sporadic outbreaks and a 10-40% case fatality rate [7].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Event Based Surveillance System of Crimean Congo Haemorrhagic Fever in Balochistan Pakistan, 2017

Ain¹,

Saeed²,

Larik³

et al. 2019

Global Biosecurity

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Background: Crimean Congo Haemorrhagic Fever (CCHF) is an acute viral zoonotic disease that is endemic in Pakistan. Poverty, limited awareness and lack of biosafety practices make it a potential occupational health risk. A poor surveillance system makes it more difficult to monitor the disease burden. Purpose: An evaluation was carried out to identify the strengths and weaknesses of the event-based CCHF surveillance system in Balochistan, Pakistan, and to propose recommendations for improvement. Methods: A descriptive evaluation study was conducted at an isolation ward of a public hospital from November 2017 to February 2018 in Balochistan Province. Event-based CCHF surveillance system was evaluated by using updated CDC guidelines for Evaluating Public Health Surveillance Systems. Data were collected through review of records and interaction with stakeholders. Using a semi-structured questionnaire, surveillance system attributes were assessed according to the guidelines in the study tool. Findings: The system was simple, but had no standardised case definition. It was found to be flexible as new healthrelated events could be easily incorporated. Data quality was moderate; 80% (75/94) of the reports were completely filled. The system had good timeliness but lacked involvement of the private sector. Acceptability was good with involvement of different government stakeholders. Sensitivity was poor while positive predictive value was 27.5%. Conclusion: Event based surveillance for CCHF can be improved by involvement of private practitioners and laboratories in the surveillance system to improve representativeness. The timeliness could be improved by adopting an online reporting mechanism. Feedback, support and supervision should be ensured for data quality assurance. Periodic refresher trainings of the staff could be organized.

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Crimean-Congo hemorrhagic fever in pregnancy: A systematic review and case series from Russia, Kazakhstan and Turkey

Cited by 37 publications

References 28 publications

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

Fluorescent Crimean-Congo hemorrhagic fever virus illuminates tissue tropism patterns and identifies early mononuclear phagocytic cell targets in Ifnar-/- mice

Crimean-Congo Hemorrhagic Fever

Evaluation of Event Based Surveillance System of Crimean Congo Haemorrhagic Fever in Balochistan Pakistan, 2017

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