Objective To investigate the effect of local injection of platelet-rich plasma (PRP) on the rate of orthodontic tooth movement. Materials and Methods Sixteen female patients were randomly allocated in a split-mouth study design to receive PRP injections with CaCl2 activating solution on one side (intervention side) while the other side received CaCl2 injection only (control side). Canine retraction was performed on 0.017 × 0.025-inch stainless steel archwire applying 1.5 N retraction force. PRP and CaCl2 injections were done at 0, 3, and 6 weeks. The duration of the study was 4 months. Data were collected from digitized models. Assessment of pain accompanying the procedure was done using a visual analogue scale. Results The rate of canine retraction was faster on the intervention side in the first 2 months, with a statistically significant difference in the first month (P = .049). On the other hand, the rate was statistically significantly slower on the intervention side in the third month following cessation of PRP injections (P = .02). Pain increased following injections on both sides. Conclusions PRP showed a positive potential to accelerate the rate of tooth movement when injected in the first 2 months. Repeated injections of PRP to maintain a steady rate of accelerated tooth movement warrant further investigation.

Local injection of PRP in the present animal study resulted in accelerated orthodontic tooth movement with no obvious clinical or microscopic side effects.

BACKGROUND: Intrusion of maxillary incisors is the treatment of choice to correct deep bite problem in gummy smile patients. AIM: The objective of this study was to compare the effectiveness and efficiency of miniscrew-supported intrusion versus intrusion arch for treatment of deep bite.METHODS: The study sample consisted of 30 post pubertal patients (21 females and 9 males) with an age range from 17 to 29. They were divided into 2 groups (15 subjects in each group). Group 1 underwent maxillary incisor intrusion using miniscrews, and in group 2 intrusive arch was used. Pre and post-treatment lateral cephalometric x-rays and study models were made to evaluate the demo-skeletal effects. During the study period, no other intervention was attempted. Paired t-test was used to study the changes after treatment.RESULTS: The mean amount of overbite correction was 2.6 ± 0.8 (0.49 mm per month) in the miniscrew-supported intrusion group and 2.9 ± 0.8 (0.60 mm per month) in the intrusive arch group. No statistically significant difference was found in the extent of maxillary incisor intrusion between the two systems. The two intrusion systems were statistically different in the extent of incisor proclination, as an intrusive arch group tended to proline upper incisors more than miniscrews-supported intrusion group.CONCLUSION: Both systems successfully intruded the 4 maxillary incisors almost with no loss to the sagittal and vertical anchorage, although intrusive arch tended to proline upper incisors significantly.

The aim of this article is to introduce a new concept of bracket positioning with special consideration to root axes. Cone-beam computed tomography imaging and computer-aided manufacturing were used to produce stereolithographic trays for indirect-direct bonding.

No abstract

AIM: Acceleration of orthodontic tooth movement has gained a massive interest to decrease the total treatment time. Local pharmacological agents might be used for that purpose as a practical, effective and inexpensive alternative. A systematic review was achieved to evaluate the evidence in that topic. METHODS: A search was conducted on electronic databases including PubMed, Lilacs, Web of Science (Thompson Reuters), EMBASE (OvidSP), and Cochrane Database of Systematic Reviews (Wiley) in addition to hand searching of relevant journals till June 2018. Only studies written in English were utilised. Publications were selected, assessed systematically and graded by two observers according to Bondemark grading system. RESULTS: Only two human studies were found investigating the effect of Relaxin and Prostaglandins in the rate of orthodontic tooth movement. No obvious side effects were reported. Relaxin showed no increase in the rate of tooth movement while prostaglandin showed a marked increase in the rate of orthodontic tooth movement. CONCLUSION: There is below moderate evidence showing no effect of relaxin on orthodontic tooth movement, while inconclusive evidence was found regarding Prostaglandin in the acceleration of orthodontic tooth movement. More prospective well-conducted clinical trials are needed to reach a proper conclusion regarding the local pharmacological agents which can be safely used to accelerate orthodontic tooth movement.

Use of this technique allowed Class II correction with concomitant reduction in the visible gingiva in the treated subjects without the adverse effects experienced with other appliances.

Objectives To compare the root resorption resulting from miniscrew-supported maxillary posterior dentoalveolar intrusion using two different force magnitudes. Materials and Methods: Adult patients with skeletal open bite, indicated for maxillary posterior dentoalveolar intrusion, were recruited and randomly assigned to the comparison or intervention groups. The comparison group involved applying 200 g of intrusive force per segment, which measured 20 g per root, while this force was 400 g per segment in the intervention group, measuring 40 g per root. Results Twenty participants were included in the final analysis after 2 patients dropped out, 1 in each group, to end up with 10 subjects (200 roots) per group. There was statistically significant root resorption of 0.84 ± 0.96 mm and 0.93 ± 1.00 mm in the comparison and the intervention groups, respectively. However, there was no statistically significant difference between the groups. Conclusions Root resorption inevitably took place in association with orthodontic intrusion. However, increasing the magnitude of the intrusive force did not increase the amount of root resorption, either statistically or clinically.