Increased urinary levels of angiotensin-converting enzyme 2 and of Ang-(1-7) in fetuses with posterior urethral valve could represent a regulatory response to the intense inflammatory process triggered by posterior urethral valve.

This study shows that inflammatory molecules are already increased in fetuses with PUV at the mean gestational age of 22 weeks, suggesting a physiopathological role for inflammation just after the embryological formation of the urethral membrane.

Congenital syngnathia is a maxillomandibular fusion, and it can vary in severity from single mucosal bands (synechiae) to complete bony fusion (synostosis). Cases of combinations of bony or soft tissue adhesions between the mandible and maxilla with cleft of the lip or palate, aglossia, popliteal pterygium, and van der Woude syndrome have been reported. It is a very rare condition, with only one case report of prenatal diagnosis using two-dimensional ultrasound in the literature. We present the first case of prenatal diagnosis of congenital syngnathia by three-dimensional ultrasound and the postnatal pathology correlation.

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Purpose The aim of this narrative review is to sumarize data about the use and role of telemedicine in maternal fetal medicine (MFM). Methods We searched pubmed and scopus to find articles about telemedicine in MFM by using the terms telmedicine or telehealth and maternal fetal medicine. Results Telehealth has been widely used for several medical specialties. During the coronavirus disease 2019 (COVID-19) pandemic, telehealth has gained investment and further research. Even though telemedicine in MFM has not been frequently applied, from 2020 onwards it has increased in both implementation and acceptance worldwide. The need to screen the patients in overloaded centers in a pandemic scenario required telemedicine in MFM, which has exhibited consistently good results concerning health and budget. The aim of this study was to review the telehealth programs and research focused on MFM around the world. Few studies have been applied to MFM and even fewer in developing and undeveloped countries. The majority of studies were concentrated in the USA and in Europe. Conclusion Further research is needed, especially in non-developed countries, to comprehend the potential role of telemedicine in MFM for improving the life quality of the patients, health professionals, and to be cost-efficient.

Electronic poster abstractsimage: 3D volume to 2D dicom images using DICOMatic (TomoVision).Step 2. Pre-processing: Gaussian filter for reducing the noise of 2D cross-section.Step 3. Iterative Binary method: applied different thresholds for each image in consideration of the characteristics of each section (2D image) to separate only the region of the fetus.Step 4. Post-processing: morphologic operation applied for segmentation of the meaningful area of the fetus.Step 5. Modeling and visualization: smoothing after surface rendering. 3D model was provided in the form of a stl file after completing all processing. Results: We applied these algorithms for 3D ultrasound volume data of fetal face and fetal heart between 19 and 29 completed gestational weeks. We successfully created 3D printing of fetal face and fetal heart with commercial 3D printer. Conclusions: Preliminary experiments indicate good results in image segmentation from 3D ultrasound data and 3D printing of fetus. It can be used for numerical analysis and creation of a physical model by 3D Printer. P24.05Contribution of magnetic resonance imaging to ultrasound for the evaluation of fetal central nervous system anomalies

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