IntroductionMeasurement of hand grip strength (HGS) has been proposed as a key component of frailty and has also been suggested as a central biomarker of healthy aging and a powerful predictor of future morbidity and mortality.Objectives(a) To determine whether a nonlinear relationship model could improve the prediction of handgrip strength (HGS) compared to the linear model and (b) to propose percentiles to evaluate HGS according to age and sex for a regional population of Chile from infancy to senescence.MethodsA cross-sectional descriptive study was developed in a representative sample of the Maule region (Chile). The volunteers amounted to 5,376 participants (2,840 men and 2,536 women), with an age range from 6 to 80 years old. Weight, height, HGS (right and left hand) according to age and sex were evaluated. Percentiles were calculated using the LMS method [(L (Lambda; asymmetry), M (Mu; median), and S (Sigma; coefficient of variation)].Results and discussionThere were no differences in HGS from 6 to 11 years of age in both sexes; however, from 12 years of age onwards, males presented higher HGS values in both hands (p < 0.05). The linear regression between age with HGS showed values of R2 = 0.07 in males and R2 = 0.02 in females. While in the non-linear model (cubic), the values were: R2 = 0.50 to 0.51 in men and R2 = 0.26 in women. The percentiles constructed by age and sex were: P5, P15, P50, P85, and P95 by age range and sex. This study demonstrated that there is a nonlinear relationship between chronological age with HGS from infancy to senescence. Furthermore, the proposed percentiles can serve as a guide to assess and monitor upper extremity muscle strength levels at all stages of life.
Background
The assessment of bone health throughout the life cycle is essential to determine fracture risk. The objectives of the work were (a) compare bone mineral density and content with international references from the United States, (b) determine maximum bone mass, (c) propose references for bone health measurements from ages 5 to 80 years old.
Methods
Research was carried out on 5,416 subjects. Weight and height were measured. Body Mass Index (BMI) was calculated. The total body was scanned using dual energy X-ray absorptiometry (DXA). Information was extracted from the bone health measures (bone mineral density (BMD) and bone mineral content (BMC)) for both sexes, according to pediatric and adult software.
Results and Discussion
Differences were identified between the mean values of Chilean and American men for BMD (~0.03 to 0.11 g/cm2) and BMC (~0.15 to 0.46 g). Chilean females showed average values for BMD similar to the US references (~−0.01 to 0.02 g/cm2). At the same time, they were relatively higher for BMC (~0.07 to 0.33 g). The cubic polynomial regression model reflected a relationship between BMD and BMC with chronological age in both sexes. For males, R2 was higher (R2 = 0.72 and 0.75) than for females (R2 = 0.59 and 0.66). The estimate of maximum bone mass (MBM) for males emerged at 30 years old (1.45 ± 0.18 g/cm2 of BMD and 3.57 ± 0.60 g of BMC) and for females at age 28 (1.22 ± 0.13 g/cm2 of BMD and 2.57 ± 0.44 g of BMC). The LMS technique was used to generate smoothed percentiles for BMD and BMC by age and sex. Results showed that maximum bone mass occurred in females at age 28 and in males at 30. Reference values obtained from this research may be used to evaluate bone health, diagnose bone fragility and osteoporosis in individuals and regional population groups.
Daily living skills may affect repetitive behavior patterns in individuals with autism spectrum disorder (ASD). This study aimed to validate a scale to assess activities of daily living at home (SAADL) in children and adolescents with ASD. Content validity by expert judgment showed Aiken V values between 0.75 and 0.88. The exploratory factor analysis (EFA) showed factor loadings (0.62 to 0.89) and high communalities. The % explanation of variance for dimension 1 (personal care) was 51.5% and for dimension 2 (mobility in the home) was 66.3%. The Cronbach's reliability was 0.87 and the retest values reflected high values of precision and accuracy. The SAADL is valid and reliable and can be used to assess activities of daily living of self-care and mobility at home.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.