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The main objective of this study was to evaluate whether the addition of curcumin‐loaded nanocapsules (prepared and characterized) in the diets of dairy sheep improved milk quality. The nanocapsules were prepared using two polymers: poly‐ε‐caprolactone (PCL) and Eudragit L‐100. The nanocapsules contained 0.25 mg/ml (Nano‐Eudragit L‐100) and 2 mg/ml (Nano‐PCL) of curcumin. Dairy sheep were divided into four groups: A (control), B (30 mg free curcumin/kg concentrate), C (3 mg Nano‐PCL/kg concentrate), and D (3 mg Nano‐Eudragit/kg concentrate). We observed that the number of total leukocytes and serum globulin levels were lower in Group D than in the control (Group A) (p < 0.05). Antioxidant capacity against peroxyl radicals (ACAP) and catalase enzymes was elevated in Group D, with consequently reduced lipid peroxidation (LPO; p < 0.05). In milk, there were no differences in production and composition between groups during the experimental period (p > 0.05); however, ACAP increased and LPO decreased in milk. Practical applications Curcumin is a functional molecule with potent antioxidant, anti‐inflammatory, and antimicrobial actions, used frequently and with medical indications in human food. Free curcumin in sheep diets improves milk quality and increases its shelf life. This study showed that curcumin nanocapsules produced from the Eudragit L‐100 polymer potentiated the anti‐inflammatory and antioxidant actions of dairy sheep when used in the diet daily, at doses 10 times lower than that of free curcumin. These positive effects were reflected in higher total antioxidant capacity and lower lipid peroxidation in milk in sheep‐fed curcumin‐loaded Eudragit L‐100 nanocapsules, generating desirable milk properties. In practice, the use of nanotechnology enhances the beneficial effects of curcumin in milk, possibly creating a nutraceutical food desirable to consumers.

ResumoOs resíduos gerados na indústria de sucos têm sido subaproveitados, desperdiçando um produto que pode apresentar potencial para ser incluído na alimentação humana. Assim, o objetivo do estudo foi realizar análise microbiológica e da composição nutricional das farinhas do resíduo de suco de uva, maçã, laranja e acerola, com diferentes granulometrias. Os resíduos da produção de suco foram obtidos através de doação de uma indústria do município de Bento Gonçalves-RS, sendo então secos e moídos para obter a farinha em diferentes granulometrias (>0,600 mm; 0,600 mm; 0,425 mm; 0,300 mm; ≤0,250 mm). As amostras de farinha foram submetidas à análise de composição centesimal, acidez, pH, Brix e polifenóis totais. As análises microbiológicas incluíram contagem de coliformes termotolerantes e pesquisa de Salmonella spp. Os resultados indicaram qualidade microbiológica satisfatória. Quanto à composição centesimal, os resultados mostraram que a granulometria influenciou o valor nutricional das farinhas e que os valores energéticos das farinhas do resíduo de acerola, laranja e uva foram inversamente proporcionais ao tamanho da partícula. Todas as farinhas analisadas podem ser consideradas ricas em fibras, cujos valores variaram de 11,2% a 54,5%. As farinhas de uva e acerola apresentaram maiores teores de proteínas, 8,2% a 15,6% e 8,3% a 12,1%, respectivamente. As farinhas do resíduo de laranja e uva apresentaram elevados teores de polifenóis totais. Portanto, o uso destes resíduos na alimentação humana pode ser recomendado, melhorando o valor nutricional de preparações. Palavras-chave: Resíduos industriais; Polifenóis; Fibra alimentar; Aproveitamento integral dos alimentos. SummaryResidues obtained from the juice industry have been underused, wasting a product that might present potential to be included in food for humans. Thus the objective of the present study was to carry out microbiological and nutritional compositional analyses of the flours made from grape, apple, orange and acerola juice residues, with different granulometries. The juice residues were obtained by donation from an industry in Bento Gonçalves (RS/Brazil), dried and ground in order to obtain flours with different granulometries (>0.600, 0.600 mm, 0.425 mm, 0.300 mm and ≤0.250 mm). The flour samples were submitted to an analysis of the proximate composition, acidity, pH, °Brix and total polyphenols. The microbiological analysis consisted of enumerating heat tolerant coliforms and testing for the presence of Salmonella spp. The results indicated satisfactory microbiological quality. The proximate composition showed that granulometry influenced the nutritional values of the flours and that the energy values of flours obtained from acerola, orange and grape residues were inversely proportional to the particle size. All the flours analysed could be considered rich in fibres, with values varying from 11.2% to 54.5%. The grape and acerola flours presented higher protein levelsfrom 8.2% to 15.6% and from 8.3% to 12.1%, respectively -and the orange and grape...

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