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This paper reviews involvement of the serotonergic system in the control of food intake and satiety. It is of great interest to understand the relevance of this system for physiological control of energy balance and obesity. Over 35 years of research suggest that serotonin (5-HT) plays an important role in satiety. Thus, the serotonergic system has been a viable target for weight control. The 5-HT has control over hunger and satiety through different receptors with distinct functions. The 5-HT2C receptor may be more important in the relationship between food intake and energy balance. This review will discuss the mechanisms of the serotonergic system involved in the control of food intake and satiety.

Mothers' low quality of life was associated with an infant in nutritional risk/malnutrition and may be a risk factor for the nutritional status of children.

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Introduction: Postoperative recovery of patients undergoing surgical procedures has been a focus of attention in recent years. Positive results from the Enhanced Recovery Based on the favorable results of the Enhanced Recovery After Surgery (ERAS) protocol, the ACERTO (Aceleração da Recuperação Total pós-operatória) protocol was designed in Brazil. This protocol defines some perioperative routines, such as nutritional therapy, decreased preoperative fasting period, early postoperative feeding, decreased venous hydration, among others, with favorable impact on postoperative recovery. The aim of this study was to compare the response of patients undergoing surgical procedures following or not a pilot protocol for accelerating postoperative recovery. Methods: A case-control study nested in a cross-sectional study reviewing medical records of patients hospitalized for colectomy, rectosigmoidectomy, pancreatectomy, and hepatectomy procedures between 2016 and 2017. The patients were divided into intervention and control group. Main endpoints analyzed were: length of postoperative hospital stay, hospitalization outcomes, rate of readmission within 30 days, and hospital costs. Results: 76 patients were enrolled (30 in intervention group and 46 in control group). The median length of in-hospital stay was 6.5 days for the intervention group and 13.5 days for the control group (p =0.0001). Rate of readmission within 30 days was 5.3 times lower in the intervention group in comparison to control group (p=0.02). Cost analysis showed a median per-patient cost of R$ 15.493,91 in the intervention group compared to a median per-patient cost of R$ 25.929,19 in the control group (p=0.0036). Conclusion: Patients who underwent the intervention of the postoperative recovery acceleration multimodal protocol presented shorter hospital stay, lower readmission rate at 30 days and lower hospital costs when compared to patients in the control group.