2011
DOI: 10.1590/s0104-42302011000100020
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Serotonina e controle hipotalâmico da fome: uma revisão

Abstract: This paper reviews involvement of the serotonergic system in the control of food intake and satiety. It is of great interest to understand the relevance of this system for physiological control of energy balance and obesity. Over 35 years of research suggest that serotonin (5-HT) plays an important role in satiety. Thus, the serotonergic system has been a viable target for weight control. The 5-HT has control over hunger and satiety through different receptors with distinct functions. The 5-HT2C receptor may b… Show more

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Cited by 17 publications
(6 citation statements)
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“…Qualquer desregulação nesses sistemas, ou até mesmo a deficiência ou diminuição dos receptores para esses peptídeos, pode influenciar o humor e o comportamento. No enfrentamento de situações estressoras ou de desgaste emocional, indivíduos que sofrem algum transtorno de humor podem aumentar o consumo de alimentos altamente palatáveis, como doces e carboidratos, de forma a compensar as deficiências provocadas pela desregulação desses hormônios [34][35][36][37].…”
Section: Discussionunclassified
“…Qualquer desregulação nesses sistemas, ou até mesmo a deficiência ou diminuição dos receptores para esses peptídeos, pode influenciar o humor e o comportamento. No enfrentamento de situações estressoras ou de desgaste emocional, indivíduos que sofrem algum transtorno de humor podem aumentar o consumo de alimentos altamente palatáveis, como doces e carboidratos, de forma a compensar as deficiências provocadas pela desregulação desses hormônios [34][35][36][37].…”
Section: Discussionunclassified
“…This is particularly important in habitats where food availability fluctuates or is unpredictable ( Schneider et al, 2013 ). In species representing every vertebrate taxa and even in some invertebrates, many putative “satiety” or “hunger” modulators including oxytocin and serotonin, function to schedule ingestive behavior in order to optimize reproductive success in environments where energy availability fluctuates ( de Matos Feijó et al, 2011 ; Schneider et al, 2013 ). The same modulators such as oxytocin and serotonin are also implicated in thermoregulation.…”
Section: Behavioral Thermoregulation and Its Physiological And Neuralmentioning
confidence: 99%
“…Serotonin influences body temperature, breathing rhythms (respiratory system), heart rate (cardiovascular function in general), eating and bowel motility (gastrointestinal system), ejaculatory latency and bladder control, muscle contraction/relaxation and locomotion, sleep, arousal, pain and sensory perception, emotions, and cognition [2, 5, 20] with a well-known signaling role in immune cells [21]. …”
Section: Serotonin As a Regulatory Molecule In Animalsmentioning
confidence: 99%
“…Knockout phenotype for 5-HT 2A shows decreased, anxiety while the one for 5-HT 2C shows increased appetite, overweight, and cognitive impairment. Serotonin receptor 5-HT 2C is probably the most important receptor related to food intake and energy balance (satiety and obesity), with viable targeting for weight control [20]. …”
Section: Serotonergic Modulation In Hippocampusmentioning
confidence: 99%