Our results suggest VM disease is more common than previously thought. We believe that further EcochG-based studies would shed light on the controversial topic on the intersection and disjunction sets of MD and VM diseases. Although the results of the present study are compatible with peripheral vestibular effects, it is not possible to rule out another central mechanism at some other level.

PURPOSE:To compared the effects of sevoflurane and desflurane on early anesthesia recovery in patients undergoing to craniotomy for intracranial lesions. METHODS:After IRB approval, the study included 50 patients aged 18-70 years who had ASA physical statuses of I-II and were scheduled for intracranial surgery. Patients were randomly divided into two groups: sevoflurane and desflurane. Anaesthesia was routinely induced in all patients followed by desflurane 5%-6% or sevoflurane 1%-2%. Moreover remifentanil infusion (0.05-0.2 mcg/ kg/min) was adjusted to maintain mean arterial pressure (MAP) within 20% baseline and heart rate <90 bpm. Postoperatively, patients were evaluated over time for responses to painful stimulus, eye opening, hand squeezing, extubation, orientation and time required to achieve a Modified Aldrete Score of 9-10. Parametric and non-parametric data were assessed using Student's t-and Mann-Whitney U tests, respectively. A p<0.05 was taken as statistically significant. RESULTS:The times to responses to painful stimuli (7.7±2.7 vs. 4.8±1.7 min.; p<0.001), emergence (9.5±2.81 vs. 6.3±2.2 min.; Early postoperative recovery after intracranial surgical procedures. Comparison of the effects of sevoflurane and desflurane

Amyloidosis is a disease of unknown etiology characterized by the accumulation of an amorphous proteinaceous material in various organs and tissues of the body. Amyloid goiter is an exceedingly rare pathologic condition due to massive amyloid infiltration of the thyroid tissue. Amyloid goiter occurs in association with both primary and secondary systemic amyloidosis, more commonly in the latter. Preoperatively, it simulates a multinodular goiter, and surgical intervention is often necessary to establish a diagnosis and to relieve compressive symptoms of a neck mass. We present the case of an 85-year-old female patient who presented with a rapidly enlarging goiter. Histologic examination confirmed amyloid goiter.

The patients with total laryngectomy seem to have more psychological problems that must be addressed in the postoperative period.

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Patients with bilateral sudden hearing loss showed lower age, worse prognosis and higher rate of positive immune response markers. Cardiovascular risk factors seem to have an important role in the aetiology of unilateral cases whereas this importance was not present in bilateral ones.

Objectives To compare voice parameters in subjects with different hearing level.Methods The evaluation consisted of Multi-Dimensional Voice Program (MDVP) and electroglottography. Group 1 consisted of normal hearing subjects which is bilateral average hearing better than 25 decibels (dB) whereas group 2 consisted of patients who have bilateral average hearing between the 25 and 60 dB and group 3 consisted of patients who have bilateral average hearing between the 60 and 90 dB. The evaluations were performed on males and females separately.Results In female subjects, fundamental frequency (F0), absolute jitter, %jitter and soft phonation index (SPI) were significantly different between the group 1 and group 2. Also, we detected significant difference on maximum phonation time (MPT), fundamental frequency, absolute jitter and %jitter, and variable F0 (vF0) values between group 1 and group 3. Male subjects demonstrated significant difference between the group 1 and group 2 in MPT, absolute jitter, %jitter, vF0, and SPI parameters. Between the group 3 and group 1; differences in absolute jitter, %jitter, shimmer, %shimmer, vF0, and SPI were also significant.Conclusion This study concluded that even mild to moderate hearing losses may affect voice patterns in adults and also females and males react differently to hearing loss in some parameters.

ÖZETAmaç: Akut intoksikasyonlar; özkıyım amaçlı veya bilinçsiz şekilde yüksek doz ilaç kullanma şeklinde olabilen önemli bir halk sağlığı sorunudur. Çalışmamızda akut intoksikasyon nedeniyle yoğun bakım ünitesinde (YBÜ) takip edilen hastaların demografik ve klinik verilerini retrospektif olarak incelemeyi amaçladık. Sonuç: Akut intoksikasyonların; büyük oranda genç kadın hastalarda, intihar amaçlı ve mevsim olarak yaz aylarında olduğunu saptadık. Analjezik ilaçların zehirlenme amacıyla en sık kullanılan ilaç olduğunu belirledik. Gereç veAnahtar Kelimeler: İntoksikasyon, yoğun bakım ünitesi, retrospektif ABSTRACT Objective: Acute intoxication is an important public health problem that occur result of suicide cases or unintentionally drug overdose. We aimed to retrospectively review the demographic and clinical data of the patients who were followed up in intensive care unit due to acute intoxication. Materials and Methods:We retrospectively reviewed the files of all 152 patients who were admitted to intensive care unit between January 2014-January 2016 due to acute intoxication. A two-sided P value <0.05 was considered significant for all analyses. Continuous variables were presented as mean ± standard deviation. Results:The 118 of 152 patients were female, 34 were male. Female to male ratio was 3.4/1. Mean age was 26.2±11.16 years. The mean length of stay in the intensive care unit was 1.85±1.05 days. The 118 of 152 (%77.6) patients were under 30 years old. The rate of intoxications were statistically lower in male than females under 30 years old. (p<0.05) Suicidal attempt was found in 145 patients (%95.32). The majority of medicine drug use was in suicide cases (%90.7). The most frequent medicine drugs were analgesics (%36.8), psychoactive drugs (%23) and antimicrobials (%19.7). %42.1 of cases were intoxicated with one drug, %48.02 of cases were intoxicated with multiple drugs. There was only one death due to pepticide poisoning. The rate of seasonal distribution of intoxications were spring (44%). The mean time to ICU admission was 292.93±201.75 minutes. Conclusion:Acute intoxications were mostly seen in especially female young female adults and the most common was suicidal attempt by medicine drugs. The most common used drugs for poisoning were analgesics.