As compared with a standard coronary stent, a sirolimus-eluting stent shows considerable promise for the prevention of neointimal proliferation, restenosis, and associated clinical events.

Objective. The measurement of aortic pulse wave velocity (PWV ao

Systematic regional sampling along the contact zone of the 1.85 Ga age Sudbury Igneous Complex with the Archean Levack Gneiss footwall in the North Range of the Sudbury structure revealed textural, mineralogical, and fluid inclusion systematics of post-Sudbury Igneous Complex hydrothermal processes that affected the various lithologies. At late stages of emplacement of the Sudbury Igneous Complex and formation of magmatic Fe-Ni-Cu sulfide deposits a partial melt from the Levack Gneiss invaded the contact zone. This partial melt is revealed by small microdikes and irregular bodies of granophyric quartz-plagioclase with megacrysts of hornblende, clinopyroxene, and titanite. Plagioclase-hornblende equilibrium was established at 750°to 800°C and 1.10 to 1.55 kbars pressure, corresponding to about a 4-to 6-km depth under lithostatic conditions. F/Cl wt percent ratios around 15 for accessory apatite and hornblende indicate that a Cl-rich fluid phase separated during the crystallization of the footwall granophyre: this is expressed as miarolites. The Cl-rich fluid (50 wt % NaCl equiv salinity) was trapped as primary fluid inclusions in quartz at around 480°C minimum temperature and around 1.1 kbars minimum pressure during supercooling. These inclusions are rich in Ca, Fe, Mn, and K, as well as Na chloride. This fluid may have interacted with earlier primary magmatic sulfide, causing remobilization and reprecipitation of Cu-Ni-platinum-group elements (PGE) in veins and disseminations in the footwall. These veins are parallel to the Sudbury Igneous Complex-footwall contact and are characterized by chalcopyrite, pentlandite, millerite, magnetite, stilpnomelane, ferropyrosmalite, epidote, and chlorite. Michenerite, moncheite, merenskyite, froodite, insizwaite, sobolevskite, gold, and Bi-Ni sulfides are associated with sulfides. Epidote, quartz, actinolite, and chlorite are common in the alteration selvages of the veins. Compositions and assemblages of platinum-group minerals (PGM) indicate their precipitation below 575°to 485°C. Primary, highly saline fluid inclusions (about 40 wt % NaCl equiv) in quartz indicate crystallization at 400°to 480°C and around 1.6 kbars minimum T and P, respectively. Late carbonate-epidote-actinolite-chlorite veins and alteration overprinted the earlier assemblages at about 300°to 400°C, with some bornite, millerite, native silver, and other Bi sulfides. The second stage of hydrothermal activity is characterized by regional carbonic-aqueous (NaCl-CO 2-CH 4-H 2 O-type) immiscible fluids that were trapped as secondary inclusions in quartz from various lithologies. No mineralization is related to this stage along the North Range. Boiling of these fluids took place during a pressure drop from lithostatic to hydrostatic conditions during uplift from about a 5-to 6-to a 3-to 4-km depth at 300°to 350°C. High-(20-26 wt % NaCl equiv) and low-salinity (6-12 wt % NaCl equiv) fluids coexisted with different carbonic species contents. The predominant north-south and northwest-southeast orientations of fluid ...

Calcite veins and related sulphate-sulphide mineralisation are common in the Buda Hills. Also, abundant hypogenic caves are found along fractures filled with these minerals pointing to the fact that young caveforming fluids migrated along the same fractures as the older mineralising fluids did. The studied vein-filling paragenesis consists of calcite, barite, fluorite and sulphides. The strike of fractures is consistent-NNW-SSEconcluding a latest Early Miocene maximum age for the formation of fracture-filling minerals. Calcite crystals contain coeval primary, hydrocarbon-bearing-and aqueous inclusions indicating that also hydrocarbons have migrated together with the mineralising fluids. Hydrocarbon inclusions are described here for the first time from the Buda Hills. Mixed inclusions, i.e., petroleum with 'water-tail', were also detected, indicating that transcrystalline water migration took place. The coexistence of aqueous and petroleum inclusions permitted to establish the entrapment temperature (80°C) and pressure (85 bar) of the fluid and thus also the thickness of sediments, having been eroded since latest Early Miocene times, was calculated (800 m). Low salinity of the fluids (\1.7 NaCl eq. wt%) implies that hydrocarbon-bearing fluids were diluted by regional karst water. FT-IR investigations revealed that CO 2 and CH 4 are associated with hydrocarbons. Groundwater also contains small amounts of HC and related gases on the basin side even today. Based on the location of the paleo-and recent hydrocarbon indications, identical migration pathways were reconstructed for both systems. Hydrocarbon-bearing fluids are supposed to have migrated north-westward from the basin east to the Buda Hills from the Miocene on.

The enhanced wave reflection in small children is a well-known phenomenon. It is explained on the basis of differences in the body height and the timing of wave reflection. This hypothesis still has not been proved directly. The aim of our study was to determine the reference values of aortic augmentation index (Aix(ao)) and the simultaneously measured return time of the systolic pulse wave (RT) in relation to the body height to test this hypothesis. Aix(ao) and RT were measured by Arteriograph in a healthy population aged 3-18 years (n = 4619, 2489 males). The Aix(ao) decreased with increasing age in boys from 18.6 ± 8.4% to 4.7 ± 4.3% and in girls from 22.3 ± 9.2% to 8.1 ± 5.1%, whereas the RT increased from 115.5 ± 16.3 ms to 166.7 ± 20.8 ms in boys and from 106.7 ± 21.9 ms to 158.1 ± 15.5 ms in girls. These changes were constant during childhood, but they slowed down after the onset of puberty. Because aortic pulse wave velocity (PWV(ao)) measured in the same population was unchanged during childhood, the increase of RT can only be explained by the increase of aortic length due to growth. In the puberty PWV(ao) starts increasing indicating that RT (Aix(ao)) does not follow the increase (decrease) of aortic length proportionally.

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