China’s hepatitis B virus (HBV) prevention policy has been evaluated through nationally representative serologic surveys conducted in 1992 and 2006. We report results of a 2014 serologic survey and reanalysis of the 1992 and 2006 surveys in the context of program policy. The 2014 survey used a 2-stage sample strategy in which townships were selected from 160 longstanding, nationally representative, county-level disease surveillance points, and persons 1–29 years of age were invited to participate. The 2014 sample size was 31,713; the response rate was 83.3%. Compared with the 1992 pre–recombinant vaccine survey, HBV surface antigen prevalence declined 46% by 2006 and by 52% by 2014. Among children <5 years of age, the decline was 97%. China’s HBV prevention program, targeted toward interrupting perinatal transmission, has been highly successful and increasingly effective. However, this progress must be sustained for decades to come, and elimination of HBV transmission will require augmented strategies.

This study quantifies the present-day global and regional distributions (2010–2014) and trends (2000–2014) for five ozone metrics relevant for short-term and long-term human exposure. These metrics, calculated by the Tropospheric Ozone Assessment Report, are: 4thhighest daily maximum 8-hour ozone (4MDA8); number of days with MDA8 > 70 ppb (NDGT70), SOMO35 (annual Sum of Ozone Means Over 35 ppb) and two seasonally averaged metrics (3MMDA1; AVGMDA8). These metrics were explored at ozone monitoring sites worldwide, which were classified as urban or non-urban based on population and nighttime lights data.Present-day distributions of 4MDA8 and NDGT70, determined predominantly by peak values, are similar with highest levels in western North America, southern Europe and East Asia. For the other three metrics, distributions are similar with North–South gradients more prominent across Europe and Japan. Between 2000 and 2014, significant negative trends in 4MDA8 and NDGT70 occur at most US and some European sites. In contrast, significant positive trends are found at many sites in South Korea and Hong Kong, with mixed trends across Japan. The other three metrics have similar, negative trends for many non-urban North American and some European and Japanese sites, and positive trends across much of East Asia. Globally, metrics at many sites exhibit non-significant trends. At 59% of all sites there is a common direction and significance in the trend across all five metrics, whilst 4MDA8 and NDGT70 have a common trend at ~80% of all sites. Sensitivity analysis shows AVGMDA8 trends differ with averaging period (warm season or annual). Trends are unchanged at many sites when a 1995–2014 period is used; although fewer sites exhibit non-significant trends. Over the longer period 1970–2014, most Japanese sites exhibit positive 4MDA8/SOMO35 trends. Insufficient data exist to characterize ozone trends for the rest of Asia and other world regions.

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a b s t r a c tTo derive O 3 doseeresponse relationships (DRR) for five European forest trees species and broadleaf deciduous and needleleaf tree plant functional types (PFTs), phytotoxic O 3 doses (PODy) were related to biomass reductions. PODy was calculated using a stomatal flux model with a range of cut-off thresholds (y) indicative of varying detoxification capacities. Linear regression analysis showed that DRR for PFT and individual tree species differed in their robustness. A simplified parameterisation of the flux model was tested and showed that for most non-Mediterranean tree species, this simplified model led to similarly robust DRR as compared to a species-and climate region-specific parameterisation. Experimentally induced soil water stress was not found to substantially reduce PODy, mainly due to the short duration of soil water stress periods. This study validates the stomatal O 3 flux concept and represents a step forward in predicting O 3 damage to forests in a spatially and temporally varying climate.Crown

Landsat-7 Enhanced Thematic Mapper Plus (ETM+) and Landsat-8 Operational Land Imager (OLI) and Thermal Infrared Sensor (TIRS) are currently operational for routine Earth observation. There are substantial differences between instruments onboard both satellites. The enhancements achieved with Landsat-8 refer to the scanning technology (replacing of whisk-broom scanners with two separate push-broom OLI and TIRS scanners), an extended number of spectral bands (two additional bands provided) and narrower bandwidths. Therefore, cross-comparative analysis is very necessary for the combined use of multi-decadal Landsat imagery. In this study, 3,311 independent sample points of four major land cover types (primary forest, unplanted cropland, swidden cultivation and water body) were used to compare the spectral bands of ETM+ and OLI. Eight sample plots with different land cover types were manually selected for comparison with the Normalized Difference Vegetation Index (NDVI), the Modified Normalized Difference Water Index (MNDWI), the Land Surface Water Index (LSWI) and the Normalized Burn Ratio (NBR). These indices were calculated with six pairs of ETM+ and OLI cloud-free images, which were acquired over the border area of Myanmar, Laos and Thailand just two days apart, when Landsat-8 achieved operational obit. Comparative results showed that: (1) the average surface reflectance of each band differed slightly, but with a high degree of similarities between both sensors. In comparison with ETM+, the OLI had higher values for the near-infrared band for vegetative land cover types, but lower values for non-vegetative types. The new sensor had lower values for the shortwave infrared (2.11-2.29 µm) band for

We report the identification of HGA in China and likely nosocomial transmission of HGA from direct contact with blood or respiratory secretions.

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